Current Issue May 2012, Vol. 103, No. 2

Issue Highlights

Systematic review

Radiation-induced cardiac damage in early left breast cancer patients: Risk factors, biological mechanisms, radiobiology, and dosimetric constraints
May 2012(Vol. 103 | No. 2 | Pages 133-142)
Angela Sardaro, Maria Fonte Petruzzelli, Maria Patrizia D’Errico, Luca Grimaldi, Giorgio Pili, Maurizio Portaluri

Original articles

Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature
May 2012(Vol. 103 | No. 2 | Pages 143-150)
Ingar Seemann, Karen Gabriels, Nils L. Visser, Saske Hoving, Johannes A. te Poele, Jeffrey F. Pol, Marion J. Gijbels, Ben J. Janssen, Fijs W. van Leeuwen, Mat J. Daemen, Sylvia Heeneman, Fiona A. Stewart

Effect of preoperative rescue concomitant FUN/XUN-based chemo-radiotherapy for neoadjuvant chemotherapy-refractory breast cancer
May 2012(Vol. 103 | No. 2 | Pages 151-154)
Céline Bourgier, Ismael Ghorbel, Steve Heymann, Manel Barhi, Chafika Mazouni, Abir Al Ghuzlan, Corinne Balleyguier, Hugo Marsiglia, Suzette Delaloge

[18F]-FDG uptake dose–response correlates with radiation pneumonitis in lung cancer patients
11 May 2012
Matthew R. McCurdy, Richard Castillo, Josue Martinez, Mohammad Najeeb Al Hallack, Jessica Lichter, Nicolas Zouain, Thomas Guerrero
Abstract: Purpose: To quantify the post-radiotherapy 2-[18F]-fluoro-2-deoxyglucose (FDG) pulmonary uptake dose–response in lung cancer patients and determine its relationship with radiation pneumoniti...
Out-of-field dose studies with an anthropomorphic phantom: Comparison of X-rays and particle therapy treatments
11 May 2012
Chiara La Tessa, Thomas Berger, Robert Kaderka, Dieter Schardt, Christine Körner, Ulla Ramm, Jörg Licher, Nakahiro Matsufuji, Christina Vallhagen Dahlgren, Tony Lomax, Günther Reitz, Marco Durante
Abstract: Background and purpose: Characterization of the out-of-field dose profile following irradiation of the target with a 3D treatment plan delivered with modern techniques. Methods: An anthropom...
Potentials of robust intensity modulated scanning proton plans for locally advanced lung cancer in comparison to intensity modulated photon plans
07 May 2012
Martin Stuschke, Andreas Kaiser, Christoph Pöttgen, Wolfgang Lübcke, Jonathan Farr
Abstract: Background and purpose: The potentials of lung sparing, dose escalation, and the robustness of intensity modulated proton plans (IMPTrobust), obtained by minimax optimization on multiple sce...
Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma
07 May 2012
Gerard Adams, Olga A. Martin, Daniel E. Roos, Pavel N. Lobachevsky, Andrew E. Potter, Andrew C. Zacest, Eva Bezak, William M. Bonner, Roger F. Martin, Trevor Leong
Abstract: Enhanced radiosensitivity is an uncommon phenomenon attributable to deficient DNA repair after radiotherapy which can be assessed with the γ-H2AX assay. Reports of radiosensitivity after ste...
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin
07 May 2012
Sebastian Reichert, Vera Reinboldt, Stephanie Hehlgans, Thomas Efferth, Claus Rödel, Franz Rödel
Abstract: Background and purpose: Novel strategies to overcome an irradiation resistant phenotype may help to increase therapeutic efficacy in glioblastoma multiforme. The present study aimed to eluci...

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Article Title	Author(s)	Type	Pages
Is it time for tailored treatment of rectal cancer? From prescribing by consensus to prescribing by numbers January 2012 (Vol. 102 \| No. 1 \| Pages 1-3) Full Text PDF (282 KB)	Vincenzo Valentini, Philippe Lambin, Robert J. Myerson	Editorial	1-3
Treatment of brain metastases: Review of phase III randomized controlled trials February 2012 (Vol. 102 \| No. 2 \| Pages 168-179) Abstract Full Text PDF (228 KB)	Silvia Scoccianti, Umberto Ricardi	Review article	168-179
Target volume delineation variation in radiotherapy for early stage rectal cancer in the Netherlands January 2012 (Vol. 102 \| No. 1 \| Pages 14-21) Abstract Full Text PDF (1488 KB) Supplemental Materials	Jasper Nijkamp, Danielle F.M. de Haas-Kock, Jannet C. Beukema, Karen J. Neelis, Dankert Woutersen, Heleen Ceha, Tom Rozema, Annerie Slot, Hanneke Vos-Westerman, Martijn Intven, Patty H. Spruit, Yvette van der Linden, Debby Geijsen, Karijn Verschueren, Marcel B. van Herk, Corrie A.M. Marijnen et al.	Full-length article	14-21
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: A phase II trial January 2012 (Vol. 102 \| No. 1 \| Pages 4-9) Abstract Full Text PDF (251 KB) Supplemental Materials	Jin-luan Li, Jia-fu Ji, Yong Cai, Xiao-fan Li, Yong-heng Li, Hao Wu, Bo Xu, Fang-yuan Dou, Zi-yu Li, Zhao-de Bu, Ai-wen Wu, Ivan W.K. Tham et al.	Full-length article	4-9
Comparison of three-dimensional versus intensity-modulated radiotherapy techniques to treat breast and axillary level III and supraclavicular nodes in a prone versus supine position January 2012 (Vol. 102 \| No. 1 \| Pages 74-81) Abstract Full Text PDF (585 KB)	Rajni A. Sethi, Hyun Soo No, Gabor Jozsef, Jane P. Ko, Silvia C. Formenti et al.	Full-length article	74-81

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Radiotherapy & Oncology publishes papers describing original research as well as review articles. It covers areas of interest relating to radiation oncology. This includes: clinical radiotherapy, combined modality treatment, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as physical aspects relevant to oncology, particularly in the field of imaging, dosimetry and radiation therapy planning.

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