The American Journal of Pathology
Volume 180, Issue 3 , Pages 929-939 , March 2012

The NF-κB Subunit c-Rel Stimulates Cardiac Hypertrophy and Fibrosis

  • Silvia Gaspar-Pereira

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Nicola Fullard

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Paul A. Townsend

      Affiliations

    • Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    • ,
  • Paul S. Banks

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Elizabeth L. Ellis

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Christopher Fox

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Aidan G. Maxwell

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Lindsay B. Murphy

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Adam Kirk

      Affiliations

    • Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    • ,
  • Ralf Bauer

      Affiliations

    • Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Jorge H. Caamaño

      Affiliations

    • Division of Immunity and Infection, Institute for BioMedical Research-Medical Research Council Centre for Immune Regulation, University of Birmingham Medical School, Birmingham, United Kingdom
    • ,
  • Nichola Figg

      Affiliations

    • Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom
    • ,
  • Roger S. Foo

      Affiliations

    • Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, University of Cambridge, Cambridge, United Kingdom
    • ,
  • Jelena Mann

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Derek A. Mann

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Fiona Oakley

      Affiliations

    • Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Corresponding Author InformationAddress reprint requests to Fiona Oakley, Ph.D., Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom

,Accepted 10 November 2011.

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 Supported by a British Heart Foundation project grant (PG/08/051/25141, FS/07/021, to D.A.M. and P.A.T.); grants from the Medical Research Council (G0900535), Wellcome Trust, and the European Union FP7 Programme (D.A.M. and F.O.); and by a Ph.D. studentship from the Gerald Kerkut Charitable Trust (S.G.-P.).

 S.G.-P. and N.F. contributed equally to the present work.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.11.007.

PII: S0002-9440(11)01070-4

doi: 10.1016/j.ajpath.2011.11.007

The American Journal of Pathology
Volume 180, Issue 3 , Pages 929-939 , March 2012

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