The American Journal of Pathology
Volume 180, Issue 3 , Pages 984-997 , March 2012

Epithelial Expression of the Cytosolic Retinoid Chaperone Cellular Retinol Binding Protein II Is Essential for in Vivo Imprinting of Local Gut Dendritic Cells by Lumenal Retinoids

  • Keely G. McDonald

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Matthew R. Leach

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Kaitlin W.M. Brooke

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Caihong Wang

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Leroy W. Wheeler

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Elyse K. Hanly

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Christopher W. Rowley

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
  • ,
  • Marc S. Levin

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
    • Department of Medicine, St. Louis VA Medical Center, St. Louis, Missouri
  • ,
  • Michael Wagner

      Affiliations

    • Department of Cell Biology, The State University of New York, Downstate Medical Center, Brooklyn, New York
  • ,
  • Ellen Li

      Affiliations

    • Department of Internal Medicine, The State University of New York, Stony Brook, New York
  • ,
  • Rodney D. Newberry

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
    • Corresponding Author InformationAddress reprint requests to Rodney Newberry, M.D., Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8124, St. Louis, MO 63110

,Accepted 14 November 2011.

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 This work was supported in part by grants DK064798 (R.D.N.), AI083538 (R.D.N.), DK085941 (L.W.W.), and DK050446 (M.S.L.). The DDRCC is supported by grant P30-DK52574. The Siteman Cancer Center is supported in part by NCI Cancer Center Support Grant P30-CA91842.

 K.G.M. and M.R.L. contributed equally to this work.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.11.009.

PII: S0002-9440(11)01072-8

doi: 10.1016/j.ajpath.2011.11.009

The American Journal of Pathology
Volume 180, Issue 3 , Pages 984-997 , March 2012