The American Journal of Pathology
Volume 180, Issue 3 , Pages 888-894 , March 2012

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin

  • Tu'uhevaha J. Kaitu'u-Lino

      Affiliations

    • Translational Obstetrics Group, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
    • Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
  • ,
  • Kirsten R. Palmer

      Affiliations

    • Translational Obstetrics Group, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
    • Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
  • ,
  • Clare L. Whitehead

      Affiliations

    • Translational Obstetrics Group, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
    • Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
  • ,
  • Elizabeth Williams

      Affiliations

    • Centre for Cancer Research, Monash Institute of Medical Research, Monash University, Clayton, Australia
  • ,
  • Martha Lappas

      Affiliations

    • Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
  • ,
  • Stephen Tong

      Affiliations

    • Translational Obstetrics Group, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
    • Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Heidelberg, Australia
    • Corresponding Author InformationAddress reprint request to Stephen Tong, Ph.D., Department of Obstetrics and Gynaecology, Mercy Hospital for Women, 163 Studley Rd., Heidelberg 3084, Victoria, Australia

,Accepted 28 November 2011.

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 Supported in part by the CASS Foundation, the Victorian Government's Operational Infrastructure Support Program, and the Medical Research Foundation for Women and Babies. The National Health and Medical Research Council of Australia provided salary (490970 to S.T.; 490995 to T.K.; 519539 to E.W.; 454777 to M.L.) and scholarship support (607219 to K.P.).

 T.J.K. and K.R.P. contributed equally to this work.

 Supplemental material for this article can be found on http://ajp.amjpathol.org; or at doi: 10.1016/j.ajpath.2011.11.014.

PII: S0002-9440(11)01077-7

doi: 10.1016/j.ajpath.2011.11.014

The American Journal of Pathology
Volume 180, Issue 3 , Pages 888-894 , March 2012