The American Journal of Pathology
Volume 180, Issue 3 , Pages 1159-1169 , March 2012

ALDH1-Bright Epithelial Ovarian Cancer Cells Are Associated with CD44 Expression, Drug Resistance, and Poor Clinical Outcome

  • Yu-Chi Wang

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Graduate Institute of Medical Sciences, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Yi-Te Yo

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Hsin-Yi Lee

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Yu-Ping Liao

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Graduate Institute of Life Sciences, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Tai-Kuang Chao

      Affiliations

    • Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Po-Hsuan Su

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Graduate Institute of Medical Sciences, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • ,
  • Hung-Cheng Lai

      Affiliations

    • Laboratory of Epigenetics and Cancer Stem Cells, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Graduate Institute of Medical Sciences, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Graduate Institute of Life Sciences, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China
    • Corresponding Author InformationAddress reprint requests to Hung-Cheng Lai, M.D., Ph.D., Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, 5F, 325, Sec 2, Cheng-Gong Rd., Neihu District, Taipei City 114, Taiwan, Republic of China

,Accepted 8 November 2011.

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 Supported by grants NHRI-EX99-9717NC (H.-C.L.) and NHRI-EX100-9717NC (H.-C.L.) from National Health Research Institutes, Taiwan, and by grants TSGH-C100-010-014-S01 (M.-H.Y.) and TSGH-C100-010-014-S02 (H.-C.L.) from Tri-Service General Hospital, Taiwan.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.11.015.

PII: S0002-9440(11)01079-0

doi: 10.1016/j.ajpath.2011.11.015

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1159-1169 , March 2012

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