The American Journal of Pathology
Volume 180, Issue 3 , Pages 1059-1067 , March 2012

Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Protein Exacerbates Collagen-Induced Arthritis by Enhancing the Expansion of Th17 Cells

  • Shengjun Wang

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
    • State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
    • Corresponding Author InformationAddress reprint requests to Shengjun Wang, M.D., Ph.D., The Affiliated People's Hospital, and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, 212013, China, or Liwei Lu, Ph.D., Department of Pathology, The University of Hong Kong, Pokfulam Road, Hong Kong, China
  • ,
  • Ye Shi

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Min Yang

      Affiliations

    • Department of Pathology and Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China
  • ,
  • Jie Ma

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Jie Tian

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Jianguo Chen

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Chaoming Mao

      Affiliations

    • Zhenjiang Key Laboratory of Medical Immunology, Affiliated Hospital of Jiangsu University, Zhenjiang, China
  • ,
  • Zhijun Jiao

      Affiliations

    • Zhenjiang Key Laboratory of Medical Immunology, Affiliated Hospital of Jiangsu University, Zhenjiang, China
  • ,
  • King-Hung Ko

      Affiliations

    • Department of Pathology and Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China
  • ,
  • Samuel Essien Baidoo

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Huaxi Xu

      Affiliations

    • Department of Laboratory Medicine, The Affiliated People's Hospital and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
  • ,
  • Zichun Hua

      Affiliations

    • State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
  • ,
  • Liwei Lu

      Affiliations

    • State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
    • Department of Pathology and Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China
    • Corresponding Author InformationAddress reprint requests to Shengjun Wang, M.D., Ph.D., The Affiliated People's Hospital, and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, 212013, China, or Liwei Lu, Ph.D., Department of Pathology, The University of Hong Kong, Pokfulam Road, Hong Kong, China

,Accepted 14 November 2011.

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 Supported by grants from the National Natural Science Foundation of China (81072453 and 30871193 to S.W., 30972748 to H.X., and 31100648 to J.M.); the National Basic Research Program of China (2010 CB 529100 to L.L.); Nanjing University State Key Laboratory of Pharmaceutical Biotechnology (KF-GN-201102 to L.L.); Graduate Student Research and Innovation Program of Jiangsu Province (CXLX11_0608 to S.E.B.); and Jiangsu Province Qinglan Project and Top Talent Program of Jiangsu University (S.W.).

 Supplemental material for this article can be found at http://ajp.amjapthol.org or at doi: 10.1016/j.ajpath.2011.11.018.

PII: S0002-9440(11)01082-0

doi: 10.1016/j.ajpath.2011.11.018

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1059-1067 , March 2012