The American Journal of Pathology
Volume 180, Issue 3 , Pages 1223-1231 , March 2012

High Anaplastic Lymphoma Kinase Immunohistochemical Staining in Neuroblastoma and Ganglioneuroblastoma Is an Independent Predictor of Poor Outcome

  • Floor A.M. Duijkers

      Affiliations

    • Department of Pediatric Oncology-Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • José Gaal

      Affiliations

    • Department of Pathology, University Medical Center, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • Jules P.P. Meijerink

      Affiliations

    • Department of Pediatric Oncology-Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • Pieter Admiraal

      Affiliations

    • Department of Pediatric Oncology-Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • Rob Pieters

      Affiliations

    • Department of Pediatric Oncology-Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • Ronald R. de Krijger

      Affiliations

    • Department of Pathology, University Medical Center, Erasmus MC, Rotterdam, the Netherlands
    • ,
  • Max M. van Noesel

      Affiliations

    • Department of Pediatric Oncology-Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
    • Corresponding Author InformationAddress reprint requests to Max M. van Noesel, M.D., Ph.D., Erasmus MC-Sophia Children's Hospital, Dr Molewaterplein 60, 3015 GJ Rotterdam, the Netherlands

,Accepted 2 December 2011.

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 Supported by Dutch Neuroblastoma Foundation Villa Joep, ODAS Foundation (Delft, the Netherlands), and a grant from The Dutch Cancer Society (2005-3452).

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.003.

PII: S0002-9440(11)01091-1

doi: 10.1016/j.ajpath.2011.12.003

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1223-1231 , March 2012

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