The American Journal of Pathology
Volume 180, Issue 3 , Pages 917-928 , March 2012

Low-Level Expression of miR-375 Correlates with Poor Outcome and Metastasis While Altering the Invasive Properties of Head and Neck Squamous Cell Carcinomas

  • Thomas Harris

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Lizandra Jimenez

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Nicole Kawachi

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Jian-Bing Fan

      Affiliations

    • Illumina Inc., San Diego, California
  • ,
  • Jing Chen

      Affiliations

    • Illumina Inc., San Diego, California
  • ,
  • Tom Belbin

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Andrew Ramnauth

      Affiliations

    • Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Olivier Loudig

      Affiliations

    • Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Christian E. Keller

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Richard Smith

      Affiliations

    • Department of Otorhinolaryngology–Head and Neck Surgery, Montefiore Medical Center, Bronx, New York
  • ,
  • Michael B. Prystowsky

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Nicolas F. Schlecht

      Affiliations

    • Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Jeffrey E. Segall

      Affiliations

    • Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Geoffrey Childs

      Affiliations

    • Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
    • Corresponding Author InformationAddress reprint requests to Geoffrey Childs, Ph.D., Albert Einstein College of Medicine, Department of Pathology, 1300 Morris Park Ave., Bronx, NY 10461

,Accepted 2 December 2011.

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 Supported in part by funds from the Department of Pathology, Albert Einstein College of Medicine and Montefiore Medical Center and by grants from the National Institutes of Health (CA77522 and CA100324 to J.E.S.). J.E.S. is the Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research.

 T.H. and L.J. contributed equally to this work. G.C. and J.E.S. are co-contributing authors.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.004

 A guest editor acted as editor-in-chief for the manuscript. No person at Albert Einstein College of Medicine or Thomas Jefferson University was involved in the peer review process or final disposition of this article.

PII: S0002-9440(11)01094-7

doi: 10.1016/j.ajpath.2011.12.004

The American Journal of Pathology
Volume 180, Issue 3 , Pages 917-928 , March 2012