The American Journal of Pathology
Volume 180, Issue 3 , Pages 1068-1079 , March 2012

Morphine Decreases Bacterial Phagocytosis by Inhibiting Actin Polymerization through cAMP-, Rac-1-, and p38 MAPK-Dependent Mechanisms

  • Jana Ninković

      Affiliations

    • Department of Pharmacology, University of Minnesota, School of Medicine, Minneapolis, Minnesota
    • ,
  • Sabita Roy

      Affiliations

    • Department of Pharmacology, University of Minnesota, School of Medicine, Minneapolis, Minnesota
    • Department of Surgery, University of Minnesota, School of Medicine, Minneapolis, Minnesota
    • Corresponding Author InformationAddress reprint requests to Sabita Roy, Ph.D., Department of Surgery, University of Minnesota, MMC 195, 420 Delaware St SE, Minneapolis, MN 55455

,Accepted 14 November 2011.

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 Supported by grants from the NIH (NIH/National Institute on Drug Abuse 5F31-DA026264 and T32 DA07097 to J.N.; RO1 DA12104, RO1 DA022935, KO2 DA015349, and P50 DA11806 to S.R.).

 CME Disclosure: None of the authors disclosed any relevant financial relationships.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.11.034.

PII: S0002-9440(11)01103-5

doi: 10.1016/j.ajpath.2011.11.034

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1068-1079 , March 2012

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