The American Journal of Pathology
Volume 180, Issue 3 , Pages 952-962 , March 2012

β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

  • Ruixia Li

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Ying Wu

      Affiliations

    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Ana Maria Manso

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Yusu Gu

      Affiliations

    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Peter Liao

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Sharon Israeli

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Toshitaka Yajima

      Affiliations

    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Uyen Nguyen

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Michael S. Huang

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Nancy D. Dalton

      Affiliations

    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Kirk L. Peterson

      Affiliations

    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • ,
  • Robert S. Ross

      Affiliations

    • Veterans Administration Healthcare, San Diego, California
    • Department of Medicine, University of California San Diego, School of Medicine, La Jolla, California
    • Corresponding Author InformationAddress reprint requests to Robert S. Ross, M.D., VA San Diego Healthcare System, 3350 La Jolla Village Dr, Cardiology Section, 111A, San Diego, CA 92161

,Accepted 2 December 2011.

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 Supported by grants from the NIH and The Veterans Administration (Merit Award) (R.S.R.).

 R.L., Y.W., and A.M.M. contributed equally to this work.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.007.

PII: S0002-9440(11)01104-7

doi: 10.1016/j.ajpath.2011.12.007

The American Journal of Pathology
Volume 180, Issue 3 , Pages 952-962 , March 2012

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