The American Journal of Pathology
Volume 180, Issue 3 , Pages 1121-1135 , March 2012

Growth Defects and Impaired Cognitive–Behavioral Abilities in Mice with Knockout for Eif4h, a Gene Located in the Mouse Homolog of the Williams-Beuren Syndrome Critical Region

  • Simona Capossela

      Affiliations

    • Gene Expression Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Luca Muzio

      Affiliations

    • Neuroimmunology Unit - INSPE, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Alessandro Bertolo

      Affiliations

    • Gene Expression Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Veronica Bianchi

      Affiliations

    • Molecular Genetics of Mental Retardation Unit, Division of Neuroscience, Dulbecco Telethon Institute, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Gabriele Dati

      Affiliations

    • INSPE, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Linda Chaabane

      Affiliations

    • INSPE, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Claudia Godi

      Affiliations

    • Neuroradiology Research Group, Center for Imaging, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Letterio S. Politi

      Affiliations

    • Neuroradiology Research Group, Center for Imaging, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Stefano Biffo

      Affiliations

    • Molecular Histology and Cell Growth Unit, Division of Molecular Oncology, San Raffaele Scientific Institute, Milan, Italy
    • Department of Science of Environment and Life (DISAV), University of Eastern Piedmont, Alessandria, Italy
  • ,
  • Patrizia D'Adamo

      Affiliations

    • Molecular Genetics of Mental Retardation Unit, Division of Neuroscience, Dulbecco Telethon Institute, San Raffaele Scientific Institute, Milan, Italy
  • ,
  • Antonello Mallamaci

      Affiliations

    • International School for Advanced Studies, SISSA, Trieste, Italy
  • ,
  • Maria Pannese

      Affiliations

    • Gene Expression Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy
    • Corresponding Author InformationAddress reprint requests to Maria Pannese, M.Sc, San Raffaele Scientific Institute, Dibit, Via Olgettina 58, 20132 Milano, Italy

,Accepted 2 December 2011.

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 Supported by grants of Fondazione Telethon GP0080Y01, and Fondazione Mariani, R-01-23; and Compagnia di San Paolo 1438IT/PF_2003.0031; and Ministero Istruzione Università e Ricerca FIRB RBAU01RN39 (A.M.); Fondazione Cariplo CAR0578 (S.B.); and Fondation Jérôme Lejeune (M.P.).

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.008.

 Current address of A.B., Swiss Paraplegic Research, Nottwil, Switzerland.

PII: S0002-9440(11)01105-9

doi: 10.1016/j.ajpath.2011.12.008

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1121-1135 , March 2012