The American Journal of Pathology
Volume 180, Issue 3 , Pages 1028-1039 , March 2012

Plasmodium falciparum Histones Induce Endothelial Proinflammatory Response and Barrier Dysfunction

  • Mark R. Gillrie

      Affiliations

    • Department of Microbiology Immunology & Infectious Diseases, University of Calgary, Alberta, Canada
    • ,
  • Kristine Lee

      Affiliations

    • Department of Microbiology Immunology & Infectious Diseases, University of Calgary, Alberta, Canada
    • ,
  • D. Channe Gowda

      Affiliations

    • Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • ,
  • Shevaun P. Davis

      Affiliations

    • Department of Microbiology Immunology & Infectious Diseases, University of Calgary, Alberta, Canada
    • ,
  • Marc Monestier

      Affiliations

    • Temple Autoimmunity Center, Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Liwang Cui

      Affiliations

    • Department of Entomology, Pennsylvania State University, University Park, Pennsylvania
    • ,
  • Tran Tinh Hien

      Affiliations

    • Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    • ,
  • Nicholas P.J. Day

      Affiliations

    • Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    • ,
  • May Ho

      Affiliations

    • Department of Microbiology Immunology & Infectious Diseases, University of Calgary, Alberta, Canada
    • Corresponding Author InformationAddress reprint requests to May Ho, M.D., Department of Microbiology and Infectious Diseases, 3330 Hospital Dr. NW, Calgary, AB, Canada T2N 4N1

,Accepted 4 November 2011.

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 Supported by a Canadian Institutes of Health Research (CIHR) grant MT14104 (M.H.). M.H. is a Scientist of Alberta Innovates-Research Solution, Canada. M.R.G. is supported by an M.D./Ph.D. scholarship from CIHR.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.11.037.

PII: S0002-9440(11)01109-6

doi: 10.1016/j.ajpath.2011.11.037

The American Journal of Pathology
Volume 180, Issue 3 , Pages 1028-1039 , March 2012

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