The American Journal of Pathology
Volume 180, Issue 4 , Pages 1386-1393 , April 2012

Ack1 Tyrosine Kinase Activation Correlates with Pancreatic Cancer Progression

  • Kiran Mahajan

      Affiliations

    • Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Domenico Coppola

      Affiliations

    • Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Y. Ann Chen

      Affiliations

    • Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Weiwei Zhu

      Affiliations

    • Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Harshani R. Lawrence

      Affiliations

    • Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Nicholas J. Lawrence

      Affiliations

    • Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Nupam P. Mahajan

      Affiliations

    • Department of Oncologic Sciences, University of South Florida, Tampa, Florida
    • Corresponding Author InformationAddress reprint requests to Nupam P. Mahajan, Ph.D., Moffitt Cancer Center, 12902 USD Magnolia Dr, SRB 22041, Tampa, FL 33612

,Accepted 22 December 2011.

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 Supported by the Chemical Biology, Tissue and Analytical Microscopy Cores at the Moffitt Cancer Center. N.P.M. is a recipient of NIH grant 1R01CA135328, a Donald A. Adam Comprehensive Melanoma Research Center Award, a Miles for Moffitt award, and Career Development Awards in Lung Cancer.

 Disclosure: K.M. and N.P.M. are named inventors on patent application No. 13/205,171, titled “AKT Tyrosine 176 Phosphorylation as Cancer Biomarker.”

 Supplemental material for this article can be found on http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.028.

PII: S0002-9440(12)00031-4

doi: 10.1016/j.ajpath.2011.12.028

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1386-1393 , April 2012

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