The American Journal of Pathology
Volume 180, Issue 4 , Pages 1394-1397 , April 2012

Atomic Identification of Fluorescent Q-Dots on Tau-Positive Fibrils in 3D-Reconstructed Pick Bodies

  • Miho Uematsu

      Affiliations

    • Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    • Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    • ,
  • Eijiro Adachi

      Affiliations

    • Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    • Department of Matrix Biology and Tissue Regeneration, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan
    • ,
  • Ayako Nakamura

      Affiliations

    • Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    • ,
  • Kuniaki Tsuchiya

      Affiliations

    • Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan
    • ,
  • Toshiki Uchihara

      Affiliations

    • Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    • Corresponding Author InformationAddress reprint requests to Toshiki Uchihara, M.D., Ph.D., Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya, Tokyo 156-8506, Japan

,Accepted 22 December 2011.

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 Supported by a Grants-in-Aid for Scientific Research grant (22500325) from the Ministry of Education, Culture, Sports, Science, and Technology, the Mitsui Life Social Welfare Foundation, and the Tokyo Metropolitan Institute of Medical Science project “Mechanism for Early Diagnosis and Prevention of Parkinson's disease.”

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi:10.1016/j.ajpath.2011.12.029.

PII: S0002-9440(12)00032-6

doi: 10.1016/j.ajpath.2011.12.029

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1394-1397 , April 2012

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