The American Journal of Pathology
Volume 180, Issue 4 , Pages 1675-1687 , April 2012

Pleiotropic Action of Renal Cell Carcinoma-Dysregulated miRNAs on Hypoxia-Related Signaling Pathways

  • Zsuzsanna Lichner

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Salvador Mejia-Guerrero

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Monika Ignacak

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Adriana Krizova

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Tian Tian Bao

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Andrew H.F. Girgis

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Yousef M. Youssef

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • George M. Yousef

      Affiliations

    • Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada
    • Corresponding Author InformationAddress reprint requests to George M. Yousef, M.D., Ph.D., F.R.C.P.C. (Path), M.Sc., M.B.B.Ch., Department of Laboratory Medicine, St. Michael's Hospital, 30 Bond St., Toronto, ON, M5B 1W8, Canada

,Accepted 27 December 2011.

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 Supported by grants from CIHR (864-90), CCS (20185), Ministry of Research and Innovation of the Government of Ontario, and the Kidney Foundation of Canada.

 Z.L. and S.M.-G. contributed equally to this work.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.030.

PII: S0002-9440(12)00033-8

doi: 10.1016/j.ajpath.2011.12.030

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1675-1687 , April 2012