The American Journal of Pathology
Volume 180, Issue 4 , Pages 1454-1464 , April 2012

DR3 Signaling Protects against Cisplatin Nephrotoxicity Mediated by Tumor Necrosis Factor

  • Rafia S. Al-Lamki

      Affiliations

    • Department of Medicine, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • National Institute for Health Research, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • Corresponding Author InformationAddress reprint requests to Rafia S. Al-Lamki, Ph.D., Department of Medicine, Level 5, Addenbrooke's Hospital, Hill's Road, Cambridge CB2 0QQ, United Kingdom
    • ,
  • WanHua Lu

      Affiliations

    • Department of Medicine, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • National Institute for Health Research, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • ,
  • Sarah Finlay

      Affiliations

    • Department of Medicine, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • ,
  • Jason P. Twohig

      Affiliations

    • Institute of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom
    • ,
  • Eddie C.Y. Wang

      Affiliations

    • Institute of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom
    • ,
  • Aviva M. Tolkovsky

      Affiliations

    • Cambridge Center for Brain Repair, University of Cambridge, Cambridge, United Kingdom
    • Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
    • ,
  • John R. Bradley

      Affiliations

    • Department of Medicine, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom
    • National Institute for Health Research, Biomedical Research Center, Addenbrooke's Hospital, Cambridge, United Kingdom

,Accepted 3 January 2012.

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 Supported by Kidney Research United Kingdom, the National Institute for Health Research Cambridge Biomedical Research Center, and the Department of Biochemistry, University of Cambridge.

 A.M.T. and J.R.B. contributed equally to this work.

 Supplemental material for this article can be found on http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2012.01.003.

PII: S0002-9440(12)00038-7

doi: 10.1016/j.ajpath.2012.01.003

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1454-1464 , April 2012

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