The American Journal of Pathology
Volume 180, Issue 4 , Pages 1688-1701 , April 2012

A Defect of the INK4-Cdk4 Checkpoint and Myc Collaborate in Blastoid Mantle Cell Lymphoma–Like Lymphoma Formation in Mice

  • Christelle Vincent-Fabert

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • ,
  • Rémi Fiancette

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • ,
  • Pauline Rouaud

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • ,
  • Christel Baudet

      Affiliations

    • EA2406, the University of Bordeaux, Bordeaux, France
    • ,
  • Véronique Truffinet

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • ,
  • Virginie Magnone

      Affiliations

    • Institut de Pharmacologie Moléculaire et Cellulaire, CNRS and the University of Nice Sophia Antipolis, UMR 6097, Sophia Antipolis, France
    • ,
  • Angélique Guillaudeau

      Affiliations

    • Pathologic Anatomy Service, CHU Dupuytren, Limoges, France
    • ,
  • Michel Cogné

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • ,
  • Pierre Dubus

      Affiliations

    • EA2406, the University of Bordeaux, Bordeaux, France
    • ,
  • Yves Denizot

      Affiliations

    • Faculty of Medicine, UMR CNRS 6101, Limoges, France
    • Corresponding Author InformationAddress reprint requests to Yves Denizot, Ph.D., Centre National de la Recherche Scientifique Unité Mixte de Recherche 6101, Laboratoire d'Immunologie, 2, rue du Dr Marcland, 87025 Limoges Cedex, France

,Accepted 3 January 2012.

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 Supported by grants from Ligue Contre le Cancer (comité départemental de la Haute-Vienne, Creuse, Corrèze, Gironde et Landes), Comité d'Organisation sur la Recherche sur le Cancer en Limousin, Conseil Régional du Limousin, ANR (Projets Blanc 2011), and “Lions Club de la Corrèze, Zone 33 district 103 Sud.” C.V.-F. was supported by a grant from the Association pour la Recherche sur le Cancer (ARC). C.B. and P.B. were supported by grants from the Région Aquitaine. The Nice Sophia-Antipolis Functional Genomics Platform was supported by MICROENVIMET, FP7-HEALTHF2-2008-201279, the ARC, and the INCa.

 R.F. and P.R. contributed equally to this work.

 Supplemental material for this article can be found at http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2012.01.004.

PII: S0002-9440(12)00039-9

doi: 10.1016/j.ajpath.2012.01.004

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1688-1701 , April 2012

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