The American Journal of Pathology
Volume 180, Issue 4 , Pages 1535-1546 , April 2012

Intestinal Mast Cell Levels Control Severity of Oral Antigen-Induced Anaphylaxis in Mice

  • Richard Ahrens

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Heather Osterfeld

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • David Wu

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Chun-Yu Chen

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Muthuvel Arumugam

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Katherine Groschwitz

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Richard Strait

      Affiliations

    • Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Division of Emergency Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Yui-Hsi Wang

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Fred D. Finkelman

      Affiliations

    • Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Simon P. Hogan

      Affiliations

    • Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Corresponding Author InformationAddress reprint requests to Simon P. Hogan, Ph.D., Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, ML7028, Cincinnati, OH 45229

,Accepted 8 December 2011.

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 Supported in part by Food Allergy Anaphylaxis Network, American Heart Foundation Midwest Affiliate, the Academy of Allergy and Asthma and Immunology Interest Section Award 2007 (S.P.H.), and NIH grants (R01AI073553-01 to S.P.H. and P30DK078392 to R.S.).

 R.A. and H.O. contributed equally to this work.

 Supplemental material for this article can be found on http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2011.12.036.

PII: S0002-9440(12)00042-9

doi: 10.1016/j.ajpath.2011.12.036

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1535-1546 , April 2012