The American Journal of Pathology
Volume 180, Issue 4 , Pages 1509-1521 , April 2012

Villin Expression Is Frequently Lost in Poorly Differentiated Colon Cancer

  • Diego Arango

      Affiliations

    • Molecular Biology and Biochemistry Research Center-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain
    • CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain
  • ,
  • Sheren Al-Obaidi

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
  • ,
  • David S. Williams

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
    • Department of Pathology, Austin Health, Melbourne, Australia
  • ,
  • Higinio Dopeso

      Affiliations

    • Molecular Biology and Biochemistry Research Center-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain
  • ,
  • Rocco Mazzolini

      Affiliations

    • Molecular Biology and Biochemistry Research Center-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain
  • ,
  • Georgia Corner

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
  • ,
  • Do-Sun Byun

      Affiliations

    • Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Azadeh A. Carr

      Affiliations

    • Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Carmel Murone

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
  • ,
  • Lars Tögel

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
  • ,
  • Nikolajs Zeps

      Affiliations

    • School of Surgery, University of Western Australia, Perth, Australia
  • ,
  • Lauri A. Aaltonen

      Affiliations

    • Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
  • ,
  • Barry Iacopetta

      Affiliations

    • School of Surgery, University of Western Australia, Perth, Australia
  • ,
  • John M. Mariadason

      Affiliations

    • Ludwig Institute for Cancer Research, Melbourne, Australia
    • Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York
    • Corresponding Author InformationAddress reprint requests to John M. Mariadason, Ph.D., Ludwig Institute for Cancer Research, Austin-Branch, Austin Health, Level 7, Harold Stokes Building, 145-163 Studley Rd., Heidelberg, Victoria 3084, Australia

,Accepted 3 January 2012.

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 This study was partially funded by grants of the Spanish Ministry of Science and Innovation (CP05/00256, TRA2009-0093 and SAF2008-00789), the Fundación Mutua Madrileña and Agència de Gestió d'Ajuts Universitaris i de Recerca (SGR 157 to D.A.). JMM is supported by a Future Fellowship from the Australian Research Council.

 Supplemental material for this article can be found on http://ajp.amjpathol.org or at doi: 10.1016/j.ajpath.2012.01.006.

PII: S0002-9440(12)00089-2

doi: 10.1016/j.ajpath.2012.01.006

The American Journal of Pathology
Volume 180, Issue 4 , Pages 1509-1521 , April 2012