| Review Article |
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Early Lymphoid Development and Microenvironmental Cues in B-cell Acute Lymphoblastic Leukemia
04 April 2012
B-cell acute lymphoblastic leukemia (B-ALL) is a hematological disorder characterized by malignant and uncontrolled proliferation of B-lymphoid precursor cells in bone marrow. Over the last few years ...
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Jessica Purizaca,
Isaura Meza,
Rosana Pelayo
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89-101
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| Original Articles |
| Biomedical |
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Osteopontin Upregulation in Atherogenesis Is Associated with Cellular Oxidative Stress Triggered by the Activation of Scavenger Receptors
14 March 2012
Background: Osteopontin (OPN) is a highly phosphorylated sialoprotein and a prominent component of mineralized extracellular matrices of bones and teeth. Although the structure of OPN has begun to be ...
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Azucena E. Jiménez-Corona,
Salvador Damián-Zamacona,
Armando Pérez-Torres,
Abel Moreno,
Jaime Mas-Oliva
et al.
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102-111
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| Clinical |
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Distortion of β-globin Chain of Hemoglobin Alters the Pathway of Erythrocytic Glucose Metabolism Through Band 3 Protein
27 February 2012
Background and Aims: Band 3 is a transmembrane protein of erythrocytes and its cytosolic part regulates glucose metabolism to proceed along the pentose phosphate pathway (PPP) or glycolytic pathway by...
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Indrani Chakraborty,
Raghwendra Mishra,
Ratan Gachhui,
Manoj Kar
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112-116
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Association of Promoter Polymorphisms in MMP2 and TIMP2 with Prostate Cancer Susceptibility in North India
27 February 2012
Background and Aims: The importance of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in tumor progression is well documented. MMP2/TIMP2 system has a significant impact on the d...
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Priyanka Srivastava,
Tasleem A. Lone,
Rakesh Kapoor,
Rama Devi Mittal
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117-124
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Intermittent Maximal Exercise Improves Attentional Performance Only in Physically Active Students
29 February 2012
Background and Aims: Regular physical activity participation seems to be linked to brain metabolism and to be one factor responsible for different effects of high intensity exercise on cognition. Due ...
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Henning Budde,
Andrea Brunelli,
Sergio Machado,
Bruna Velasques,
Pedro Ribeiro,
Oscar Arias-Carrión,
Claudia Voelcker-Rehage
et al.
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125-131
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Lymphatic Microvessel Density Combined with CT Used in the Diagnosis of Mediastinal and Hilar Lymph Node Metastasis of Non-small Cell Lung Cancer
01 March 2012
Background and Aims: Lymphatic microvessel density (LMVD) has been demonstrated to correlate with tumor metastasis. The purpose of this study is to determine whether the criteria combining LMVD with c...
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Hui Zhou,
Jin-Kang Liu,
Shen-Xi Chen,
Zeng Xiong,
Guo-Qiang Lin,
Mo-Ling Zhou,
Wei Chen,
Yang-Teng-Yu Liu
et al.
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132-138
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Effectiveness of Silver-enhanced In Situ Hybridization for Evaluating HER2 Gene Status in Invasive Breast Carcinoma: A Comparative Study
03 April 2012
Background and Aims: HER2 gene amplification occurs in breast cancers and has implications for treatment and prognosis. Recently, a new direct evaluation technique, silver enhanced in situ hybridizati...
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Youngseok Lee,
Youngjoon Ryu,
Hoiseon Jeong,
Hyeyoon Chang,
Younghye Kim,
Aeree Kim
et al.
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139-144
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| Epidemiological |
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Adiponectin Level and Gene Variability Are Obesity and Metabolic Syndrome Markers in a Young Population
27 February 2012
Background and Aims: Human obesity is accepted as an important risk factor for development of MetS. Adiponectin is linked to central obesity and ADIPOQ variants are promising markers for understanding...
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Ivana Karmelić,
Jasna Lovrić,
Tamara Božina,
Hana Ljubić,
Željka Vogrinc,
Nada Božina,
Jadranka Sertić
et al.
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145-153
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Association Between Val158Met Functional Polymorphism in the COMT Gene and Risk of Preeclampsia in a Chinese Population
03 April 2012
Background and Aims: The catechol-O-methyltransferase (COMT) gene is a potential candidate in altering risk for preeclampsia due to the important enzymatic effects in the metabolism of steroid hormone...
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Shanshan Liang,
Xinghui Liu,
Ping Fan,
Rui Liu,
Juan Zhang,
Guolin He,
Yu Liu,
Huai Bai
et al.
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154-158
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Airflow Obstruction in Never Smokers in Five Latin American Cities: The PLATINO Study
03 April 2012
Background: Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD ...
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Rogelio Perez-Padilla,
Rosario Fernandez,
Maria Victorina Lopez Varela,
Maria Montes de Oca,
Adriana Muiño,
Carlos Tálamo,
José Roberto Brito Jardim,
Gonzalo Valdivia,
Ana Maria Baptista Menezes
et al.
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159-165
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| Letters to the Editor |
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Association Between MTHFR C677T Polymorphism and Diabetic Nephropathy in a Chinese Population: Appraisal of a Recent Meta-analysis
27 February 2012
I read with great interest the recent paper by Cui et al. . The authors performed a meta-analysis of 12 case-control studies to examine the association of the C677T polymorphism in methylenetetrahydro...
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Yan-Feng Zou
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166-167
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Reply: Is the C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
14 March 2012
We are grateful to the authors who shared their comments and suggestions about the Letter to the Editor regarding several limitations of our meta-analysis . After reviewing the author’s comments and c...
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Wen-Peng Cui,
Bing Du,
Ye Jia,
Wen-Hua Zhou,
Sheng-Mao Liu,
Ying-Chun Cui,
Fu-Zhe Ma,
Ping Luo,
Li-Ning Miao
et al.
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168-169
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Need for Clarification of Data in the Recent Meta-analysis About 1858 C/T Polymorphism of the Protein Tyrosine Phosphatase Nonreceptor 22 Gene and Rheumatoid Arthritis Risk
05 April 2012
Recently, we have read with great interest the article “1858 C/T Polymorphism of the Protein Tyrosine Phosphatase Nonreceptor 22 Gene and Rheumatoid Arthritis Risk in Europeans: A Meta-analysis based ...
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Zhi-Hua Zhang,
Lin-Sheng Yang,
Ye-Huan Sun
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170-171
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Reply: Clarification of Data from 1858 C/T Polymorphism of the Protein Tyrosine Phosphatase Nonreceptor 22 Gene and Rheumatoid Arthritis Risk in Europeans: A Meta-analysis
05 April 2012
Thank you very much for forwarding me the Letter to the Editor. After reviewing the comments and checking the original papers and the raw data carefully, we are glad to reply and to clarify their ques...
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Ren Ke-Wei,
Mi Yuan-Yuan,
Xu Nan-Wei
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172
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| Frontmatter |
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Editorial Board
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A1
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Table of Contents
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A2-A3
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