| Mini-reviews |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Antiangiogenic agents as second-line therapy for advanced non-small cell lung cancer
23 February 2012
Abstract: With the approval of the antiangiogenic antibody bevacizumab in non-small cell lung cancer (NSCLC) and other malignancies, the tumor vasculature has emerged as a worthwhile therapeutic targe...
|
Karen L. Reckamp
|
101-109
|
|
|
|
Mucins and Toll-like receptors: Kith and kin in infection and cancer
26 April 2012
Abstract: Inflammation is underlying biological phenomenon common in infection and cancer. Mucins are glycoproteins which establish a physical barrier for undesirable entry of foreign materials throug...
|
Shikha Tarang,
Sushil Kumar,
Surinder K. Batra
|
110-119
|
|
| Regular Articles |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells
29 March 2012
Abstract: Targeted photosensitizer delivery to EGFR-expressing cells was achieved in the present study using a high purity, targeted photoimmunoconjugate (PIC). When the PDT agent, benzoporphyrin deri...
|
Adnan O. Abu-Yousif,
Anne C.E. Moor,
Xiang Zheng,
Mark D. Savellano,
Weiping Yu,
Pål K. Selbo,
Tayyaba Hasan
et al.
|
120-127
|
|
|
|
Sunitinib synergizes the antitumor effect of cisplatin via modulation of ERCC1 expression in models of gastric cancer
22 March 2012
Abstract: We evaluated the effects of sunitinib monotherapy and in combination with cisplatin in human gastric cancer cell lines. Sunitinib showed antiproliferative effect in gastric cancer cells line...
|
Young-Kwang Yoon,
Seock-Ah Im,
Ahrum Min,
Hwang-Phill Kim,
Hyung-Seok Hur,
Kyung-Hun Lee,
Sae-Won Han,
Sang-Hyun Song,
Do Youn Oh,
Tae-You Kim,
Woo Ho Kim,
Yung-Jue Bang
et al.
|
128-136
|
|
|
|
Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cells
23 March 2012
Abstract: Cisplatin can induce apoptosis in ovarian cancer cells through the mitochondrial death pathway, and dysregulation of this pathway contributes to cisplatin resistance in ovarian cancer cells....
|
Xiaokui Yang,
Jiandong Wang,
Ying Zhou,
Yamei Wang,
Shuyu Wang,
Weiyuan Zhang
et al.
|
137-143
|
|
|
|
Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells
23 April 2012
Abstract: Ginsenoside F2 (F2) was assessed for its antiproliferative activity against breast cancer stem cells (CSCs). F2 induced apoptosis in breast CSCs by activating the intrinsic apoptotic pathway...
|
Trang Thi Mai,
JeongYong Moon,
YeonWoo Song,
Pham Quoc Viet,
Pham Van Phuc,
Jung Min Lee,
Tae-Hoo Yi,
Moonjae Cho,
Somi Kim Cho
et al.
|
144-153
|
|
|
|
Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation
27 February 2012
Abstract: Hepatitis C virus Core plays a vital role in the development of hepatocellular carcinoma; however, the mechanism is still controversial. Here, we show that Core overcomes premature senescenc...
|
Joo Song Lim,
Sun-Hye Park,
Kyung Lib Jang
|
154-161
|
|
|
|
A microRNA signature differentiates between giant cell tumor derived neoplastic stromal cells and mesenchymal stem cells
27 February 2012
Abstract: Giant cell tumor (GCT) derived stromal cells (GCTSCs) have been identified as the neoplastic cell population of GCTs. Within these stromal cells a subpopulation has been identified that shar...
|
Joerg Fellenberg,
Heiner Saehr,
Burkhard Lehner,
Daniela Depeweg
|
162-168
|
|
|
|
Calcineurin subunit B promotes TNF-alpha-induced apoptosis by binding to mitochondria and causing mitochondrial Ca2+ overload
23 February 2012
Abstract: Previous studies have shown that excess calcineurin subunit B (CnB) associates with mitochondria. Here, CnB overexpression increased CN activity in cells and enhanced TNF-alpha-induced cell ...
|
Jinbo Cheng,
Wei Tang,
Zhenyi Su,
Junxia Guo,
Li Tong,
Qun Wei
et al.
|
169-178
|
|
|
|
Effectiveness of a combination therapy using calcineurin inhibitor and mTOR inhibitor in preventing allograft rejection and post-transplantation renal cancer progression
05 March 2012
Abstract: Calcineurin inhibitors (CNIs) may promote post-transplantation cancer through altered expression of cytokines and chemokines in tumor cells. We found that there is a potential cross-talk amo...
|
Aninda Basu,
Tao Liu,
Pallavi Banerjee,
Evelyn Flynn,
David Zurakowski,
Dipak Datta,
Ondrej Viklicky,
Martin Gasser,
Ana Maria Waaga-Gasser,
Jun Yang,
Soumitro Pal
et al.
|
179-186
|
|
|
|
The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells
05 March 2012
Abstract: The ability to induce changes in cell membrane properties is nowadays considered an additional mechanism to explain the pharmacological effects of non-steroidal anti-inflammatory drugs (NSAI...
|
Simona Tavolari,
Alessandra Munarini,
Gianluca Storci,
Stefan Laufer,
Pasquale Chieco,
Tiziana Guarnieri
et al.
|
187-194
|
|
|
|
Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes
19 March 2012
Abstract: Med1/TRAP220 is an essential component of the TRAP/Mediator complex. In this study, we present a novel function of Med1 in human non-small-cell lung cancer (NSCLC) progression. We found that...
|
Hyun-Ju Kim,
Mee Sook Roh,
Choon Hee Son,
Ae Jeong Kim,
Hye Jin Jee,
Naree Song,
Minjee Kim,
Su-Young Seo,
Young Hyun Yoo,
Jeanho Yun
et al.
|
195-202
|
|