Contemporary Clinical Trials is the new title for the previously published journal, Controlled Clinical Trials. This title change reflects the evolution in design and process for clinical trials that has occurred since the journal was originally launched in 1980. Contemporary Clinical Trials is an international journal that publishes manuscripts pertaining to the design, methods and operational aspects of clinical trials. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioral science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words in the following subject areas will be published:

• Unusual design features of specific trials that may be applicable to other studies
• Organizational structures that facilitate multicenter investigations
• General or specific design and operating features of data processing systems used for maintaining data bases in clinical trials
• Medical, legal, and ethical issues in the conduct of clinical trials
• Management of multicenter investigations
• Methods for assessing patient adherence
• Design of case report forms and other data collection methods for clinical trials
• Quality assurance procedures for error detection in the data generation and processing procedures in clinical trials
• Data auditing practices in clinical trials
• Methods for collecting and reporting adverse event data in clinical trials
• Regulatory requirements for clinical trials
• Patient involvement in the design of clinical trials
• Statistical methods for clinical trials
• Historical review of clinical trials
• Methods and case examples of monitoring clinical trials for evidence of adverse or beneficial treatment effects
• Cost assessment of procedures used for data generation, processing, and auditing in clinical trials
• Assessment of the impact of clinical trials on the practice of medicine.