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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Listeria infection in patients on anti-TNF treatment: Report of two cases and review of the literature
DOI: 10.1016/j.crohns.2012.04.018
Abstract: Listeria monocytogenes is an aerobic gram positive intracellular bacillus, predominantly affecting pregnant women, immunocompromised patients and old individuals. Invasive listeriosis, menin...
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Cândida Abreu,
Fernando Magro,
Filipe Vilas-Boas,
Susana Lopes,
Guilherme Macedo,
António Sarmento
et al.
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Short communication
(In Press Corrected Proof)
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24 May 2012 |
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Cutaneous vasculitis in ulcerative colitis mimicking Henoch–Schönlein purpura
DOI: 10.1016/j.crohns.2012.05.001
Abstract: To the best of our knowledge, no cases of ulcerative colitis (UC) mimicking Henoch–Schönlein purpura (HSP) have been reported so far. During a 28-year period 5635 patients were followed up a...
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Guilherme Trudes de Oliveira,
Sofia Simão Martins,
Mariana Deboni,
Patrícia Picciarelli,
Lúcia Maria Arruda Campos,
Adriana Almeida Jesus,
Yu Kar Ling Koda,
Clovis Artur Silva
et al.
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Short communication
(In Press Corrected Proof)
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24 May 2012 |
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Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy
DOI: 10.1016/j.crohns.2012.04.019
Abstract: Background and aims: Inflammatory bowel disease, a chronic inflammation of the intestinal tract, presents in two variations, Ulcerative Colitis (UC) and Crohn's disease (CD). Given that trea...
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Natasha S. Stephens,
Jesse Siffledeen,
Xiaorong Su,
Travis B. Murdoch,
Richard N. Fedorak,
Carolyn M. Slupsky
et al.
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Full-length article
(In Press Corrected Proof)
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24 May 2012 |
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Economic impact of combination therapy with infliximab plus azathioprine for drug-refractory Crohn's disease: A cost-effectiveness analysis
DOI: 10.1016/j.crohns.2012.04.007
Abstract: Background: Combination therapy with infliximab (IFX) and azathioprine (AZA) is significantly more effective for treatment of active Crohn's disease (CD) than IFX monotherapy. However, AZA i...
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Shota Saito,
Utako Shimizu,
Zhang Nan,
Nozomu Mandai,
Junji Yokoyama,
Kenshi Terajima,
Kouhei Akazawa
et al.
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Full-length article
(In Press Corrected Proof)
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24 May 2012 |
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A patient with ulcerative colitis and central serous chorioretinopathy—A therapeutic dilemma
DOI: 10.1016/j.crohns.2012.04.020
Abstract: We report a case of a patient with ulcerative colitis and central serous retinopathy, which is a chronic ophthalmological condition that is frequently aggravated by corticosteroid treatment ...
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Bella Geyshis,
Gabriel Katz,
Shomron Ben-Horin,
Uri Kopylov
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Short communication
(In Press Corrected Proof)
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23 May 2012 |
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Causality in administrative datasets
DOI: 10.1016/j.crohns.2012.04.014
We read with great interest the original contribution by Ananthakrishnan et al. on the effect of infection-related hospitalizations in patients with inflammatory bowel diseases on mortality, hospital ...
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Julia McNabb-Baltar,
Quoc-Dien Trinh
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Correspondence
(In Press Corrected Proof)
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21 May 2012 |
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Management of inflammatory bowel disease in pregnancy
DOI: 10.1016/j.crohns.2012.04.009
Abstract: Background and Aims: Inflammatory bowel disease (IBD) is a chronic disease affecting mainly young people in their reproductive years. IBD therefore has a major impact on patients’ family pla...
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Séverine Vermeire,
Franck Carbonnel,
Pierre G. Coulie,
Vincent Geenen,
Johanna M.W. Hazes,
Pierre L. Masson,
Filip De Keyser,
Edouard Louis
et al.
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Review article
(In Press Corrected Proof)
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18 May 2012 |
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Reply to Dr. Chouchana's letter
DOI: 10.1016/j.crohns.2012.04.013
We would like to thank Dr. Chouchana for the comments on our manuscript and thereby giving us the opportunity to discuss this important topic again.
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Ulf Hindorf,
Malin Lindqvist Appell
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Correspondence
(In Press Corrected Proof)
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17 May 2012 |
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Reply to Dr. McNabb-Baltar's letter
DOI: 10.1016/j.crohns.2012.04.012
We thank the interest shown in our manuscript by Dr. McNabb-Baltar and agree that identification of risk factors for infectious complications in patients with inflammatory bowel disease (IBD) is an im...
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Ashwin N. Ananthakrishnan
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Correspondence
(In Press Corrected Proof)
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17 May 2012 |
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Proinflammatory cytokines induce crosstalk between colonic epithelial cells and subepithelial myofibroblasts: Implication in intestinal fibrosis
DOI: 10.1016/j.crohns.2012.04.008
Abstract: Background and aims: Colonic epithelial cells and adjacent subepithelial myofibroblasts are important counterparts in the pathogenesis of intestinal inflammation and fibrosis. We investigate...
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Ioannis Drygiannakis,
Vassilis Valatas,
Ourania Sfakianaki,
Leonidas Bourikas,
Pinelopi Manousou,
Konstantinos Kambas,
Konstantinos Ritis,
George Kolios,
Elias Kouroumalis
et al.
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Full-length article
(In Press Corrected Proof)
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11 May 2012 |
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The “hygiene hypothesis” in IBD
DOI: 10.1016/j.crohns.2012.04.010
We read with interest the paper by Castiglione et al. investigating the role of hygiene hypothesis related as potential risk factors for the development of inflammatory bowel disease (IBD). This study...
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Richard B. Gearry,
Andrew J. Dodgshun
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Correspondence
(In Press Corrected Proof)
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07 May 2012 |
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Positive serum IgA-tissue-transglutaminase antibodies are not all but enough to diagnose coeliac disease without a small bowel biopsy
DOI: 10.1016/j.crohns.2012.04.002
We have read with great interest the article by Fernández-Bañares and coworkers about the attitude of the tissue-transglutaminase antibodies of IgA class (tTG) in implementing the diagnosis of celiac ...
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Fabio Panetta,
Francesca Ferretti,
Antonella Diamanti
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Correspondence
(In Press Corrected Proof)
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03 May 2012 |
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Elevated immunoglobulin G4 level is associated with reduced colectomy-free survival in patients with primary sclerosing cholangitis and ulcerative colitis
DOI: 10.1016/j.crohns.2012.04.006
Abstract: Background and aim: Patients with primary sclerosing cholangitis (PSC) and elevated immunoglobulin (Ig) G4 have been shown to have more severe disease with a shorter time to orthotopic liver...
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Udayakumar Navaneethan,
Preethi GK Venkatesh,
Maria Choudhary,
Bo Shen,
Ravi P. Kiran
et al.
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Full-length article
(In Press Corrected Proof)
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03 May 2012 |
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Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: A case report and a short review of the literature
DOI: 10.1016/j.crohns.2012.04.005
Abstract: Primary sclerosing cholangitis is a chronic progressive disorder which involves the medium size and large ducts in the intrahepatic and extrahepatic biliary tree. The great majority of cases...
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María Chaparro,
María Trapero-Marugán,
Mercedes Guijarro,
Consuelo López,
Ricardo Moreno-Otero,
Javier P. Gisbert
et al.
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Short communication
(In Press Corrected Proof)
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01 May 2012 |
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Reply to Dr. Panetta et al.'s letter
DOI: 10.1016/j.crohns.2012.04.004
Panetta et al. describe that a tTG value of around 3×upper normal limit (using an ELISA commercial kit by Liaison, DiaSorin S.p.a., Salugia, Italy) was associated with a post-test probability of celia...
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Fernando Fernández-Bañares,
Mercé Rosinach,
Maria Esteve
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Correspondence
(In Press Corrected Proof)
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30 April 2012 |
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TPMT status determination: The simplest is the most effective?
DOI: 10.1016/j.crohns.2012.04.003
We carefully read the article by Hindorf and Appell stating that genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase (TPMT) function. As evi...
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Laurent Chouchana,
Celine Narjoz,
Marie-Anne Loriot
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Correspondence
(In Press Corrected Proof)
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30 April 2012 |
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Contrast-enhanced ultrasonography: Usefulness in the assessment of postoperative recurrence of Crohn's disease
DOI: 10.1016/j.crohns.2012.03.017
Abstract: Aim: The aim of this study was to assess whether the contrast-enhanced ultrasonography (CEUS) can increase the value of the ultrasonography in the study of postoperative recurrence of Crohn'...
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José María Paredes,
Tomás Ripollés,
Xavier Cortés,
Nadia Moreno,
María Jesús Martínez,
Marco Bustamante-Balén,
Fructuoso Delgado,
Eduardo Moreno-Osset
et al.
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Full-length article
(In Press Corrected Proof)
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30 April 2012 |
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Incidence of inflammatory bowel disease in the province of Styria, Austria, from 1997 to 2007: A population-based study
DOI: 10.1016/j.crohns.2012.03.012
Abstract: Background: The incidence of inflammatory bowel disease (IBD) varies widely between different countries. This large variation is also observed for the incidence of its main two forms, ulcera...
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W. Petritsch,
S. Fuchs,
A. Berghold,
G. Bachmaier,
C. Högenauer,
A.C. Hauer,
U. Weiglhofer,
H.H. Wenzl
et al.
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Full-length article
(In Press Corrected Proof)
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30 April 2012 |
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Immunohistochemical search for viral and bacterial antigens in Crohn's disease
DOI: 10.1016/j.crohns.2012.03.021
Abstract: Background: Recent studies show that diseased intestinal tissues of patients with Crohn's disease (CD) contain obstructed lymphatics, granulomas, and tertiary lymphoid organs, representing r...
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William S. Magin,
Herbert J. Van Kruiningen,
Jean-Frédéric Colombel
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Full-length article
(In Press Corrected Proof)
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27 April 2012 |
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Previous infliximab therapy and postoperative complications after proctocolectomy with ileum pouch anal anastomosis
DOI: 10.1016/j.crohns.2012.03.013
Abstract: Background and aims: It is unclear whether infliximab treatment induces increased complication rates after surgery for ulcerative colitis. Aim was to compare complication rates after pouch s...
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Emma J. Eshuis,
Rana L. Al Saady,
Pieter C.F. Stokkers,
Cyriel Y. Ponsioen,
Pieter J. Tanis,
Willem A. Bemelman
et al.
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Full-length article
(In Press Corrected Proof)
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27 April 2012 |
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Does active smoking really influence the course of Crohn's disease? A retrospective observational study
DOI: 10.1016/j.crohns.2012.03.020
Abstract: Background: Active smoking has been associated with a higher risk of developing Crohn's disease (CD). However, its impact on clinical outcomes has been controversial among studies. Aims: To ...
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Yamile Zabana,
Esther Garcia-Planella,
Manuel Van Domselaar,
Míriam Mañosa,
Jordi Gordillo,
Antonio López San Román,
Eduard Cabré,
Eugeni Domènech
et al.
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Full-length article
(In Press Corrected Proof)
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27 April 2012 |
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Probable diffuse retinopathy caused by adalimumab in a patient with Crohn's disease
DOI: 10.1016/j.crohns.2012.03.015
Abstract: Adalimumab is a tumor necrosis factor-α (TNF-α) antagonist used to treat several immunologic diseases. It is believed that unexpected adverse events related to anti-TNF drugs will occur as a...
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Paula Marticorena-Álvarez,
María Chaparro,
Andrés Pérez-Casas,
Aurora Muriel-Herrero,
Javier P. Gisbert
et al.
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Short communication
(In Press Corrected Proof)
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26 April 2012 |
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Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patients
DOI: 10.1016/j.crohns.2012.03.018
Abstract: Background and aims: Adalimumab is efficacious in inducing and maintaining remission in Crohn's disease but dose escalation is needed in 30–40% after 1year. Attempts for dose de-escalation h...
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Filip Baert,
Elien Glorieus,
Cathérine Reenaers,
Geert D'Haens,
Harald Peeters,
Dennis Franchimont,
Olivier Dewit,
Philippe Caenepeel,
Edouard Louis,
Gert Van Assche,
for BIRD (Belgian IBD Research and Development)
et al.
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Full-length article
(In Press Corrected Proof)
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26 April 2012 |
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Reply to Dr. Vitek's letter
DOI: 10.1016/j.crohns.2012.03.019
We thank you for the opportunity to respond to the interesting letter by Dr. Vitek, regarding our results on the common UGT1A1*28 allele in the UGT1A1 gene which is related to hyperbilirubinemia and i...
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Hilbert S. de Vries,
Wilbert H.M. Peters,
Dirk J. de Jong
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Correspondence
(In Press Corrected Proof)
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25 April 2012 |
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Severe adalimumab-induced thrombocytopenia in a patient with Crohn's disease
DOI: 10.1016/j.crohns.2012.04.001
Abstract: Crohn's disease is a chronic transmural inflammatory disorder characterized by inflammation of the intestine. Anti-TNF-α drugs are used for induction and maintenance of remission in patients...
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M.J. Casanova,
M. Chaparro,
S. Martínez,
I. Vicuña,
J.P. Gisbert
et al.
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Short communication
(In Press Corrected Proof)
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25 April 2012 |
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Single port laparoscopic subtotal colectomy and ileostomy in an adolescent with ulcerative colitis
DOI: 10.1016/j.crohns.2012.03.011
Abstract: Introduction: Single port laparoscopic surgery has been increasingly used for complex surgical procedures. To our knowledge, this is the first published report of a single port laparoscopic ...
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Nikolaos A. Chatzizacharias,
Franco Torrente,
Mary Brennan,
Robert Heuschkel,
R. Justin Davies
et al.
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Short communication
(In Press Corrected Proof)
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20 April 2012 |
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Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis
DOI: 10.1016/j.crohns.2012.03.016
Abstract: Introduction: Adalimumab is a recombinant human IgG1 monoclonal antibody to TNF-alpha. There are limited data with regard to its efficacy in ulcerative colitis. We report experience of adali...
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Edel McDermott,
Seamus Murphy,
Denise Keegan,
Diarmuid O'Donoghue,
Hugh Mulcahy,
Glen Doherty
et al.
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Full-length article
(In Press Corrected Proof)
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20 April 2012 |
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Low mannose-binding lectin (MBL) is associated with paediatric inflammatory bowel diseases and ileal involvement in patients with Crohn disease
DOI: 10.1016/j.crohns.2012.03.008
Abstract: Background: Mannose-binding lectin (MBL) is a pattern-recognition molecule of the innate immune system and may be involved in the pathogenesis of inflammatory bowel disease (IBD). Our aim wa...
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Marta Kovacs,
Maria Papp,
Peter Laszlo Lakatos,
Silvia Jacobsen,
Eva Nemes,
Marianne Polgar,
Eniko Solyom,
Piroska Bodi,
Agnes Horvath,
Kriszta Molnar,
Doloresz Szabo,
Aron Cseh,
Katalin Eszter Muller,
Antal Dezsofi,
Andras Arato,
Gabor Veres
et al.
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Full-length article
(In Press Corrected Proof)
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16 April 2012 |
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Inflammatory bowel disease and lupus: A systematic review of the literature
DOI: 10.1016/j.crohns.2012.03.005
Abstract: Coexistence of systemic lupus erythematosus (SLE) should be considered in patients with inflammatory bowel disease (IBD) and complex extraintestinal manifestations and the diagnosis of IBD c...
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Konstantinos H. Katsanos,
Paraskevi V. Voulgari,
Epameinondas V. Tsianos
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Review article
(In Press Corrected Proof)
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16 April 2012 |
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Schaumann bodies in Crohn's disease: a case report and review of the literature
DOI: 10.1016/j.crohns.2012.03.009
Abstract: Schaumann bodies are inclusion bodies, first described by Schaumann in 1941, typically seen in granulomatous diseases such as tuberculosis, sarcoidosis and chronic beryllium diseases. Willia...
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Luisa Lorenzi,
Zeno Bisoffi,
Laura Bortesi,
Giuseppe Zamboni,
Francesca Liut,
Vincenzo Villanacci
et al.
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Short communication
(In Press Corrected Proof)
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13 April 2012 |
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Clinical status, psychosocial impairments, medical treatment and health care costs for patients with inflammatory bowel disease (IBD) in Germany: An online IBD registry
DOI: 10.1016/j.crohns.2012.02.014
Abstract: Background: The aim of this cross-sectional study was to establish an online inflammatory bowel disease (IBD) registry for a first picture of the situation of IBD outpatients' treatment in G...
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B. Bokemeyer,
J. Hardt,
D. Hüppe,
A. Prenzler,
S. Conrad,
M. Düffelmeyer,
P. Hartmann,
M. Hoffstadt,
T. Klugmann,
C. Schmidt,
J. Weismüller,
T. Mittendorf,
H. Raspe
et al.
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Full-length article
(In Press Corrected Proof)
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13 April 2012 |
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Effectiveness of contrast-enhanced ultrasound for characterisation of intestinal inflammation in Crohn's disease: A comparison with surgical histopathology analysis
DOI: 10.1016/j.crohns.2012.03.002
Abstract: Background: Differentiation between predominantly inflammatory versus fibrous-predominant lesions is particularly important in order to decide the optimal therapy in patients with refractory...
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Tomás Ripollés,
Nuria Rausell,
Jose M. Paredes,
Enrique Grau,
María J. Martínez,
Jose Vizuete
et al.
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Full-length article
(In Press Corrected Proof)
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09 April 2012 |
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Serum bilirubin levels and the risk of Crohn's disease
DOI: 10.1016/j.crohns.2012.03.010
I have read with great interest a recent study by Drs. de Vries and colleagues on the association between UGT1A1 promoter gene variants and a decreased risk of Crohn's disease (CD). The authors have d...
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Libor Vítek
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Correspondence
(In Press Corrected Proof)
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06 April 2012 |
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Risedronate improves bone mineral density in Crohn's disease: A complementary mechanism
DOI: 10.1016/j.crohns.2012.03.014
I read with great interest the paper by Soo and colleagues entitled “Risedronate improves bone mineral density in Crohn's disease: A two year randomized controlled clinical trial.” This work addressed...
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Hamid Namazi
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Correspondence
(In Press Corrected Proof)
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06 April 2012 |
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Adalimumab improves patient-reported outcomes and reduces indirect costs in patients with moderate to severe Crohn's disease: Results from the CARE trial
DOI: 10.1016/j.crohns.2012.02.017
Abstract: Background and aims: Crohn's disease negatively affects patients’ quality of life and ability to work. We investigated the impact of adalimumab on work productivity, daily activities, and qu...
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Edouard Louis,
Robert Löfberg,
Walter Reinisch,
Anne Camez,
Mei Yang,
Paul F. Pollack,
Naijun Chen,
Jingdong Chao,
Parvez M. Mulani
et al.
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Full-length article
(In Press Corrected Proof)
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06 April 2012 |
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Long-term outcome of tumor necrosis factor alpha antagonist's treatment in pediatric Crohn's disease
DOI: 10.1016/j.crohns.2012.03.006
Abstract: Background: Anti tumor necrosis factor alpha (TNFα) agents have become widely used in pediatric inflammatory bowel disease (IBD). So far, only few studies examined the long-term results of a...
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Amit Assa,
Corina Hartman,
Batia Weiss,
Efrat Broide,
Yoram Rosenbach,
Noam Zevit,
Yoram Bujanover,
Raanan Shamir
et al.
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Full-length article
(In Press Corrected Proof)
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06 April 2012 |
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Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: Case report and review of the literature
DOI: 10.1016/j.crohns.2012.03.004
Abstract: Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is we...
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Filipe Vilas-Boas,
Fernando Magro,
Rui Balhau,
José M. Lopes,
Francisco Beça,
Catarina Eloy,
Susana Lopes,
Guilherme Macedo
et al.
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Short communication
(In Press Corrected Proof)
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05 April 2012 |
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Prevalence and natural history of hepatitis B and C infections in a large population of IBD patients treated with anti-tumor necrosis factor-α agents
DOI: 10.1016/j.crohns.2012.03.001
Abstract: Background: The prevalence rates of hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients with inflammatory bowel disease (IBD) have been reported to be higher than rates of infect...
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Alfredo Papa,
Carla Felice,
Manuela Marzo,
Gianluca Andrisani,
Alessandro Armuzzi,
Marcello Covino,
Giammarco Mocci,
Daniela Pugliese,
Italo De Vitis,
Antonio Gasbarrini,
Gian Lodovico Rapaccini,
Luisa Guidi
et al.
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Full-length article
(In Press Corrected Proof)
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05 April 2012 |
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Serum anti-Müllerian hormone levels are lower in reproductive-age women with Crohn's disease compared to healthy control women
DOI: 10.1016/j.crohns.2012.03.003
Abstract: Background and aim: Crohn’s disease (CD) decreases fertility both directly, by inducing inflammation in the fallopian tubes and ovaries, and indirectly, through the surgical interventions an...
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Ebubekir Şenateş,
Yaşar Çolak,
Emrullah Düzgün Erdem,
Atakan Yeşil,
Ender Coşkunpınar,
Önder Şahin,
Mustafa Erhan Altunöz,
Ilyas Tuncer,
Ayşe O. Kurdaş Övünç
et al.
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Full-length article
(In Press Corrected Proof)
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03 April 2012 |
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Tolerability of one hour 10 mg/kg infliximab infusions in patients with inflammatory bowel disease
DOI: 10.1016/j.crohns.2012.03.007
Abstract: Background and aim: In patients with inflammatory bowel disease (IBD) tolerating 2-h infusions of 5mg/kg infliximab scheduled maintenance therapy, the infusion time can be shortened to 1-h w...
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Abdenour Babouri,
Anthony Buisson,
Marc-André Bigard,
Laurent Peyrin-Biroulet
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Full-length article
(In Press Corrected Proof)
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03 April 2012 |
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A rare case of pericarditis, complication of infliximab treatment for Crohn's disease
DOI: 10.1016/j.crohns.2012.02.016
Infliximab, a monoclonal anti-TNFα antibody, is a widely used drug in the treatment of inflammatory bowel disease. Various adverse reactions including infusion reactions, reactivation of tuberculosis,...
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Joe Devasahayam,
Unnikrishnan Pillai,
Alexandre Lacasse
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Correspondence
(In Press Corrected Proof)
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30 March 2012 |
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TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in Inflammatory Bowel Disease
DOI: 10.1016/j.crohns.2012.02.020
Abstract: Background and aims: Genome-wide association (GWA) studies recently identified a novel gene, TRAF3IP2, involved in the susceptibility to psoriasis. Common immune-mediated mechanisms involvin...
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Cinzia Ciccacci,
Livia Biancone,
Davide Di Fusco,
Micaela Ranieri,
Giovanna Condino,
Emiliano Giardina,
Sara Onali,
Tiziana Lepre,
Francesco Pallone,
Giuseppe Novelli,
Paola Borgiani
et al.
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Full-length article
(In Press Corrected Proof)
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27 March 2012 |
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The risk of contracting pediatric inflammatory bowel disease in children with celiac disease, epilepsy, juvenile arthritis and type 1 diabetes—a nationwide study
DOI: 10.1016/j.crohns.2012.02.021
Abstract: Background and aims: The association of celiac disease with inflammatory bowel disease (IBD) in children is unclear. This study assesses the risk of IBD in children diagnosed with celiac dis...
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Lauri J. Virta,
Kaija-Leena Kolho
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Full-length article
(In Press Corrected Proof)
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27 March 2012 |
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Increased titers of anti-Saccharomyces cerevisiae antibodies in Crohn's disease patients with reduced H-ficolin levels but normal MASP-2 activity
DOI: 10.1016/j.crohns.2012.02.013
Abstract: Background and aims: Mannan-binding lectin (MBL) and ficolins are microbial pattern recognition molecules that activate the lectin pathway of complement. We previously reported the associati...
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Thomas Schaffer,
Beatrice Flogerzi,
Alain M. Schoepfer,
Frank Seibold,
Stefan Müller
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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Reversible Henoch–Schönlein purpura complicating adalimumab therapy
DOI: 10.1016/j.crohns.2012.02.019
Abstract: The tumour necrosis factor antagonists have demonstrated efficacy in the induction of remission and its maintenance in numerous chronic inflammatory conditions. These agents are generally we...
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Inês Marques,
Ana Lagos,
Jorge Reis,
António Pinto,
Beatriz Neves
et al.
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Short communication
(In Press Corrected Proof)
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23 March 2012 |
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Infection-related hospitalizations are associated with increased mortality in patients with inflammatory bowel diseases
DOI: 10.1016/j.crohns.2012.02.015
Abstract: Introduction: Serious infections are an important side effect of immunosuppressive therapy used to treat Crohn's disease (CD) and ulcerative colitis (UC). There have been no nationally repre...
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Ashwin N. Ananthakrishnan,
Emily L. McGinley
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Full-length article
(In Press Corrected Proof)
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22 March 2012 |
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Adalimumab for the prevention and/or treatment of post-operative recurrence of Crohn's disease: A prospective, two-year, single center, pilot study
DOI: 10.1016/j.crohns.2012.02.012
Abstract: Background: Infliximab has shown efficacy at preventing post operative recurrence (POR) of Crohn's disease (CD). This study aimed at evaluating whether adalimumab can prevent and treat POR o...
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Konstantinos Papamichael,
Emmanuel Archavlis,
Constantina Lariou,
Gerassimos J. Mantzaris
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Full-length article
(In Press Corrected Proof)
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19 March 2012 |
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Detection of CMV in pouch mucosa in a patient with acute pouchitis: The real enemy or an innocent bystander?
DOI: 10.1016/j.crohns.2012.02.011
A 30-year-old woman was diagnosed with fulminant UC in 2003 during lactation. She underwent proctocolectomy with ileal pouch–anal anastomosis due to intractable symptoms and conservative treatment fai...
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Georgios Tribonias,
Konstantinos Karmiris,
Elpida Giannikaki,
Konstantinos Konstantinidis,
Evangelos Voudoukis,
Angeliki Theodoropoulou,
Emmanouil Vardas,
Gregorios A. Paspatis
et al.
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Correspondence
(In Press Corrected Proof)
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14 March 2012 |
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Elevated levels of serum-soluble triggering receptor expressed on myeloid cells-1 in patients with IBD do not correlate with intestinal TREM-1 mRNA expression and endoscopic disease activity
DOI: 10.1016/j.crohns.2012.02.010
Abstract: Background & aims: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory responses. We have previously demonstrated a substantial increase i...
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Leslie Saurer,
Silvia Rihs,
Michèle Birrer,
Nikolina Saxer-Seculic,
Markus Radsak,
Christoph Mueller,
The Swiss IBD Cohort Study
et al.
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Full-length article
(In Press Corrected Proof)
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14 March 2012 |
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A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis
DOI: 10.1016/j.crohns.2012.02.004
Abstract: In recent years, the use of antibodies against tumor necrosis factor α (TNFα) has expanded in rheumatology, gastroenterology, and dermatology. In addition to the more common side effects suc...
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Urpo Kinnunen,
Martti Färkkilä,
Heikki Mäkisalo
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Short communication
(In Press Corrected Proof)
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05 March 2012 |
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The efficacy of intensive granulocyte and monocyte adsorption apheresis in a patient with Crohn's disease complicated by extensive subcutaneous aseptic neutrophilic abscesses
DOI: 10.1016/j.crohns.2012.02.005
Abstract: Background and aims: Subcutaneous aseptic abscess is one phenotype of neutrophilic dermatitis. We were interested to see if a case of steroid refractory Crohn's disease (CD) complicated by s...
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Shingo Kato,
Eriko Hosomi,
Fumi Amano,
Taisuke Kobayashi,
Kazuhito Kani,
Ryuichi Yamamoto,
Tomonari Ogawa,
Akihiko Matsuda,
Yoshiki Sato,
Seiichi Izaki,
Tetsuya Mitarai,
Koji Yakabi
et al.
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Short communication
(In Press Corrected Proof)
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05 March 2012 |
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Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol
DOI: 10.1016/j.crohns.2012.02.007
Abstract: Background and aims: Azathioprine and mercaptopurine remain first line immunomodulatory treatments for inflammatory bowel disease. Toxicity and non-response are significant issues. Co-prescr...
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Melissa A. Smith,
Paul Blaker,
Anthony M. Marinaki,
Simon H. Anderson,
Peter M. Irving,
Jeremy D. Sanderson
et al.
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Full-length article
(In Press Corrected Proof)
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05 March 2012 |
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Enteroendocrine cells in terminal ileal Crohn's disease
DOI: 10.1016/j.crohns.2012.01.013
Abstract: Background and aims: Enteroendocrine cells sense gut luminal contents, and orchestrate digestive physiology whilst contributing to mucosal homeostasis and innate immunity. The terminal ileum...
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Gordon W. Moran,
Joanne Pennock,
John T. McLaughlin
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Full-length article
(In Press Corrected Proof)
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02 March 2012 |
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Primary tuberculous peritonitis during infliximab therapy for Crohn's disease
DOI: 10.1016/j.crohns.2012.02.003
Abstract: A 64year old male patient suffering from Crohn’s disease received infliximab therapy for a period of 5months prior to presentation to our hospital. Due to the symptoms fever, ascites, and di...
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Ulrich Bonse-Geuking,
Michael Kraus
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Short communication
(In Press Corrected Proof)
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29 February 2012 |
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Circulating MicroRNA in inflammatory bowel disease
DOI: 10.1016/j.crohns.2012.02.006
Abstract: Background: MicroRNAs (miRNAs) consist of a group of small noncoding RNAs that partially regulate gene expression. We investigated the expression patterns of commonly deregulated miRNAs in C...
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Archanioti Paraskevi,
George Theodoropoulos,
Ioannis Papaconstantinou,
Gerassimos Mantzaris,
Nikolaos Nikiteas,
Maria Gazouli
et al.
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Full-length article
(In Press Corrected Proof)
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29 February 2012 |
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Histopathological characterization of cholecystectomy specimens in patients with inflammatory bowel disease
DOI: 10.1016/j.crohns.2012.02.002
Abstract: Background and aims: Inflammatory bowel disease is associated with increased risk of cholelithiasis. However, the histologic patterns in gallbladders have not been extensively studied. This ...
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Jingmei Lin,
Bo Shen,
Hwa-Jeong Lee,
John R. Goldblum
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Full-length article
(In Press Corrected Proof)
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29 February 2012 |
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“Ulcerative crepitus” — A case with subcutaneous emphysema and pneumomediastinum without colonic perforation or toxic megacolon in ulcerative colitis successfully treated conservatively
DOI: 10.1016/j.crohns.2012.01.022
Abstract: A 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea and severe dehidration. He was on po.48mg methylprednisolon and 3g mesalazine daily, and h...
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Anita Annaházi,
Ilona Polyák,
Ferenc Nagy,
Tibor Wittmann,
Tamás Molnár
et al.
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Short communication
(In Press Corrected Proof)
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27 February 2012 |
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Is patient reported outcome (PRO) affected by different follow-up regimens in inflammatory bowel disease (IBD)? A one year prospective, longitudinal comparison of nurse-led versus conventional follow-up
DOI: 10.1016/j.crohns.2012.01.021
Abstract: Objective: Specialist nurses have become increasingly involved in the management of Inflammatory Bowel Disease (IBD). The objectives of this study were to investigate the impact of nurse-led...
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Lars-Petter Jelsness-Jørgensen,
Tomm Bernklev,
Magne Henriksen,
Roald Torp,
Bjørn Moum
et al.
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Full-length article
(In Press Corrected Proof)
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27 February 2012 |
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Anti-TNF therapy induced immune neutropenia in Crohns disease- report of 2 cases and review of literature
DOI: 10.1016/j.crohns.2012.01.014
Abstract: Transient neutropenia is reported in some patients on biologic therapy. We report two cases of severe neutropenia in patients with Crohn`s disease following treatment with anti-TNF therapy. ...
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Shaji Sebastian,
Katherine Ashton,
Yasmine Houston,
Tina Mary Diggory,
Philip Dore
et al.
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Short communication
(In Press Corrected Proof)
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27 February 2012 |
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The requirements and barriers to successful transition of adolescents with inflammatory bowel disease: Differing perceptions from a survey of adult and paediatric gastroenterologists
DOI: 10.1016/j.crohns.2012.01.010
Abstract: Background and aim: Preliminary data highlight the importance of appropriate transition for successful transfer of adolescents with IBD from paediatric to adult care. The aim of this study w...
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Shaji Sebastian,
Huw Jenkins,
Sarah McCartney,
Tariq Ahmad,
Ian Arnott,
Nick Croft,
Richard Russell,
James O. Lindsay
et al.
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Full-length article
(In Press Corrected Proof)
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27 February 2012 |