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Editorial Board
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The Editor's Choice
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173-174
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| Preface |
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A mini-symposium of 2nd Japanese Society for Investigative Dermatology-Asia-Oceania-Forum
Self and non-self (auto or non-autoimmune), inflammation and immunity, complexity and simplicity, and their interrelationships have been attracting researchers. The major interest is the difference be...
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Fukumi Furukawa
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175
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| Invited Review articles |
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The suppressive effects of ultraviolet radiation on immunity in the skin and internal organs: Implications for autoimmunity
25 January 2012
Abstract: Low doses of sunlight that can be received during normal daily activities suppress immunity in humans. Both ultraviolet (UV) B (290–320nm) and UVA (320–400nm) are immunosuppressive. The wave...
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Gary M. Halliday,
Diona L. Damian,
Sabita Rana,
Scott N. Byrne
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176-182
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Rare hereditary autoinflammatory disorders: Towards an understanding of critical in vivo inflammatory pathways
15 February 2012
Abstract: Hereditary autoinflammatory syndromes are monogenic disorders with an inborn error of innate immunity, and include periodic fever syndromes such as familial Mediterranean fever (FMF), tumor ...
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Nobuo Kanazawa
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183-189
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Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis
27 April 2012
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) are rare but life-threatening severe cutaneous adverse reactions (SCARs), which are majorly (65–75%) induced by a variety of...
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Wen-Hung Chung,
Shuen-Iu Hung
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190-196
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| Regular articles |
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HOXA5 inhibits keratinocytes growth and epidermal formation in organotypic cultures in vitro and in vivo
05 April 2012
Abstract: Background: Homeobox transcription factors play important roles in epidermal renewal. Among them HOXA5 emerges as a promising member. However, its direct effect on epidermal biology, either ...
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Yimin Liang,
Lingling Xia,
Zijing Du,
Lingling Sheng,
Huili Chen,
Gang Chen,
Qingfeng Li
et al.
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197-206
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Kojic acid-induced IL-6 production in human keratinocytes plays a role in its anti-melanogenic activity in skin
05 April 2012
Abstract: Background: Kojic acid is a fungal metabolite widely used in medicinal and cosmetic formulations as a skin-lightening agent based on its de-pigmenting activity. Although in human clinical st...
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Hyunjung Choi,
Kwangmi Kim,
Jiyeon Han,
Hyun Choi,
Sun Hee Jin,
Eun Kyung Lee,
Dong Wook Shin,
Tae Ryong Lee,
Ai-Young Lee,
Minsoo Noh
et al.
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207-215
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Changes in photoinduced cutaneous erythema with topical application of a combination of vitamins C and E before and after UV exposure
26 April 2012
Abstract: Background: Ultraviolet radiation is harmful for human skin, and photodamaging pathologies such as actinic erythema, are formerly described as a consequence of UV direct effect on DNA and in...
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José Aguilera,
María Victoria de Gálvez,
Cristina Sánchez,
Enrique Herrera-Ceballos
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216-220
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Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma
05 April 2012
Abstract: Background: Although topical photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) is applied for skin tumors including actinic keratosis, Bowen disease, and squamous cell carcinoma, ...
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Hidetoshi Takahashi,
Susumu Nakajima,
Ryuji Asano,
Yoshinori Nakae,
Isao Sakata,
Hajime Iizuka
et al.
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221-224
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Relationship between microstructure of the skin surface and surface reflection based on geometric optics
20 April 2012
Abstract: Background: The behavior of reflected light in skin affects skin appearance and provides clues as to the internal condition of the skin. Surface topography is one of the central physical fac...
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Kenichiro Yoshida,
Masahiro Miyaki,
Nobutoshi Ojima,
Kayoko Iwata
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225-232
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Long TSLP transcript expression and release of TSLP induced by TLR ligands and cytokines in human keratinocytes
20 April 2012
Abstract: Background: Thymic stromal lymphopoietin (TSLP), highly expressed in keratinocytes in atopic dermatitis patients and bronchial epithelial cells in asthma patients, plays a key role in allerg...
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Yang Xie,
Toshiro Takai,
Xue Chen,
Ko Okumura,
Hideoki Ogawa
et al.
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233-237
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| Letters to the editor |
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Biological contribution of UVA wavelengths in non extreme daily UV exposure
05 April 2012
Chronic sun exposure leads to long term clinical skin alterations such as photoaging and photocarcinogenesis, involving both ultraviolet B (UVB) (280–320nm) and UVA (320–400nm) wavelengths. To study t...
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Claire Marionnet,
François Lejeune,
Cécile Pierrard,
Corinne Vioux-Chagnoleau,
Françoise Bernerd
et al.
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238-240
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Assessment of BRAF and KIT mutations in Japanese melanoma patients
25 April 2012
BRAF- and KIT-activating mutations are established therapeutic targets in melanoma. In a recent trial, the BRAF inhibitor vemurafenib improved survival in patients with the BRAFV600E mutation . Simila...
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Atsuko Ashida,
Hisashi Uhara,
Yukiko Kiniwa,
Misae Oguchi,
Hiroshi Murata,
Yasufumi Goto,
Aya Uchiyama,
Eisaku Ogawa,
Koichi Hayashi,
Hiroshi Koga,
Ryuhei Okuyama
et al.
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240-242
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Decreased repair of singlet oxygen-induced DNA damage in xeroderma pigmentosum group A cells determined by plasmid host cell reactivation
29 February 2012
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Shinichi Moriwaki,
Yoshito Takahashi,
Hiroko Shimizu,
Mayumi Inoue,
Yoshinori Sugiyama,
Shintaro Inoue
et al.
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242-244
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Eleven novel mutations of the ADAR1 gene in dyschromatosis symmetrica hereditaria
16 February 2012
Dyschromatosis symmetrica hereditaria (DSH: MIM#127400) shows an autosomal dominant pattern of inheritance with high penetrance, which is characterized by hyperpigmented and hypopigmented macules on t...
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Masakazu Kawaguchi,
Masahiro Hayashi,
Ichidai Murata,
Yutaka Hozumi,
Noriyuki Suzuki,
Yoshiyuki Ishii,
Mari Wataya-Kaneda,
Yoko Funasaka,
Tamihiro Kawakami,
Kazuyoshi Fukai,
Toyoko Ochiai,
Chikako Nishigori,
Yoshihiko Mitsuhashi,
Tamio Suzuki
et al.
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244-245
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