| Breast cancer |
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Training breast care nurses throughout Europe: The EONS postbasic curriculum for breast cancer nursing
25 August 2011
Abstract: Background: The European Parliamentary Group on Breast Cancer and the European Society of Breast Cancer Specialists state that there is a need for EU agreed guidelines on breast care nursing...
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Manuela Eicher,
Ilana Kadmon,
Saskia Claassen,
Sara Marquard,
Emma Pennery,
Yvonne Wengstrom,
Deborah Fenlon
et al.
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1257-1262
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Body image and psychological distress after prophylactic mastectomy and breast reconstruction in genetically predisposed women: A prospective long-term follow-up study
21 November 2011
Abstract: Purpose: To explore the course of psychological distress and body image at long-term follow-up (6–9years) after prophylactic mastectomy and breast reconstruction (PM/BR) in women at risk for...
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Mariska den Heijer,
Caroline Seynaeve,
Reinier Timman,
Hugo J. Duivenvoorden,
Kathleen Vanheusden,
Madeleine Tilanus-Linthorst,
Marian B.E. Menke-Pluijmers,
Aad Tibben
et al.
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1263-1268
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| Gastrointestinal oncology |
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Type 2 diabetes mellitus and colorectal cancer: Meta-analysis on sex-specific differences
02 September 2011
Abstract: Although there is consent concerning a higher risk for colorectal cancer (CRC) amongst patients with type 2 diabetes mellitus (T2DM), there remains uncertainty regarding potential sex differ...
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Heike U. Krämer,
Ben Schöttker,
Elke Raum,
Hermann Brenner
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1269-1282
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Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer
21 November 2011
Abstract: Background: Annualised figures show an up to 7-fold higher incidence of vascular thromboembolism (VTE) in patients with advanced pancreatic cancer (APC) compared to other common malignancies...
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A. Maraveyas,
J. Waters,
R. Roy,
D. Fyfe,
D. Propper,
F. Lofts,
J. Sgouros,
E. Gardiner,
K. Wedgwood,
C. Ettelaie,
G. Bozas
et al.
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1283-1292
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Impact of age on choice of chemotherapy and outcome in advanced colorectal cancer
28 November 2011
Abstract: Background: Age is a major risk factor for development of sporadic colorectal cancer but elderly patients are underrepresented in clinical trials and are potentially offered chemotherapy les...
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Muhammad A. Khattak,
Amanda R. Townsend,
Carol Beeke,
Christos S. Karapetis,
Colin Luke,
Rob Padbury,
Guy Maddern,
David Roder,
Timothy J. Price
et al.
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1293-1298
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| Lung cancer |
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Lung cancer in never smokers – A review
30 March 2012
Abstract: An estimated 10–25% of lung cancers worldwide occur in never smokers, i.e. individuals having smoked less than 100 cigarettes in their lifetime. Lung cancer in never smokers (LCINS) is more ...
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Sébastien Couraud,
Gérard Zalcman,
Bernard Milleron,
Franck Morin,
Pierre-Jean Souquet
et al.
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1299-1311
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| Urologic oncology |
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Effect of family history on outcome in German patients treated with radical prostatectomy for clinically localised prostate cancer
07 November 2011
Abstract: Objective: The outcome of prostate cancer (CaP) patients treated with radical prostatectomy (RP) might be influenced by family history (FH) in a subset of patients. We analysed the effect of...
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Matthias M. Heck,
Martina Kron,
Jürgen E. Gschwend,
Kathleen Herkommer
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1312-1317
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Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy
14 March 2012
Abstract: Aim: We investigated the prognostic significance of intraductal carcinoma of the prostate (IDC-P) in biopsies and transurethral resections prior to external beam radiotherapy with or without...
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T. Van der Kwast,
N. Al Daoud,
L. Collette,
J. Sykes,
J. Thoms,
M. Milosevic,
R.G. Bristow,
G. Van Tienhoven,
P. Warde,
R.-O. Mirimanoff,
M. Bolla
et al.
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1318-1325
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Long term renal toxicity of ifosfamide in adult patients – 5 year data
16 April 2012
Abstract: Ifosfamide is indicated as first line treatment in a variety of solid tumours in adults. It is known to be nephrotoxic and is often used following therapy with, or as concomitant therapy wit...
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James K. Farry,
Carlos D. Flombaum,
Sheron Latcha
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1326-1331
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| Gynecologic oncology |
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Evaluation of paclitaxel/carboplatin in a dose dense or weekly regimen in 66 patients with recurrent or primary metastatic cervical cancer
10 February 2012
Abstract: Background and aims: To evaluate paclitaxel/carboplatin in a dose dense (TCdd) and weekly (TCw) regimen in recurrent or primary metastatic cervical cancer. Methods: Six courses of paclitaxel...
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Sofie Torfs,
Isabelle Cadron,
Frederic Amant,
Karin Leunen,
Patrick Berteloot,
Ignace Vergote
et al.
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1332-1340
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| Head and neck cancer |
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Population-based evidence of increased survival in human papillomavirus-related head and neck cancer
19 April 2012
Abstract: Background: Evidence from clinical, population-based and molecular studies has shown that human papillomavirus (HPV) infection can be a causal risk factor for a subset of head and neck squam...
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Mari Nygård,
Bjarte Aagnes,
Freddie Bray,
Bjørn Møller,
Jon Mork
et al.
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1341-1346
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| Sarcoma |
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Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma
23 April 2012
Abstract: Background: Activation of the mammalian target of rapamycin (mTOR) pathway has been demonstrated in sarcoma. Trials using mTOR inhibitor in sarcoma have shown low objective response rates bu...
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Scott M. Schuetze,
Lili Zhao,
Rashmi Chugh,
Dafydd G. Thomas,
David R. Lucas,
Gino Metko,
Mark M. Zalupski,
Laurence H. Baker
et al.
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1347-1353
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| Advanced cancers |
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Prognostic value of circulating VEGFR2+ bone marrow-derived progenitor cells in patients with advanced cancer
27 February 2012
Abstract: We hypothesised that host-related markers, possibly reflecting tumour aggressiveness, such as circulating endothelial cells (CEC) and circulating VEGFR2+ bone marrow-derived (BMD) progenitor...
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Christophe Massard,
Isabelle Borget,
Marie Cécile Le Deley,
Melissa Taylor,
Carlos Gomez-Roca,
Jean Charles Soria,
Françoise Farace
et al.
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1354-1362
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| Pediatric oncology |
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Treatment-related mortality in children with acute myeloid leukaemia in Central America: Incidence, timing and predictors
15 November 2011
Abstract: Background: Cure rates in paediatric acute myeloid leukaemia in low-income countries lag behind those in high-income countries, in part secondary to higher rates of treatment-related mortali...
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Sumit Gupta,
Miguel Bonilla,
Patricia Valverde,
Ligia Fu,
Scott C. Howard,
Raul C. Ribeiro,
Lillian Sung
et al.
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1363-1369
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Synovial sarcoma in children and adolescents: A critical reappraisal of staging investigations in relation to the rate of metastatic involvement at diagnosis
10 February 2012
Abstract: Background: European protocols for paediatric synovial sarcoma (SS) require that all children routinely undergo chest computed tomography (CT) scanning and bone scanning as initial staging p...
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Andrea Ferrari,
Gian Luca De Salvo,
Odile Oberlin,
Michela Casanova,
Angela De Paoli,
Annie Rey,
Véronique Minard,
Daniel Orbach,
Modesto Carli,
Bernadette Brennan,
Max M. Vannoesel,
Carlo Morosi,
Michael C. Stevens,
Gianni Bisogno
et al.
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1370-1375
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Risk adapted chemotherapy for localised Ewing’s sarcoma of bone: The French EW93 study
19 April 2012
Abstract: Aim of the study: To determine whether a risk factor adapted chemotherapy would improve the outcome of non-metastatic bone Ewing’s sarcoma. Methods: Standard risk tumours (SR, good histologi...
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Nathalie Gaspar,
Annie Rey,
Perrine Marec Bérard,
Jean Michon,
Jean Claude Gentet,
Marie Dominique Tabone,
Henri Roché,
Anne Sophie Defachelles,
Odile Lejars,
Emmanuel Plouvier,
Claudine Schmitt,
Binh Bui,
Patrick Boutard,
Sophie Taque,
Martine Munzer,
Jean-Pierre Vannier,
Dominique Plantaz,
Natacha Enz-Werlé,
Odile Oberlin
et al.
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1376-1385
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| Clinical trial design |
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Adaptive designs at European Organisation for Research and Treatment of Cancer (EORTC) with a focus on adaptive sample size re-estimation based on interim-effect size
27 January 2012
Abstract: Given the high failure rates and the increased costs of Phase III trials in oncology and the recent explosion of targeted agents, researchers are looking for better design strategies to try ...
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M. Mauer,
L. Collette,
J. Bogaerts,
European Organisation for Research and Treatment of Cancer (EORTC) Statistics Department
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1386-1391
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| Guidelines |
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Cancer guideline development in Europe: A survey among ECCO members
13 February 2012
Abstract: A survey was conducted among European Cancer Organisations by the European CanCer Organisation (ECCO) to evaluate initiatives on cancer guideline development. An electronic questionnaire bas...
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Dirk Schrijvers,
Marco Rosselli Del Turco,
Carol Maddock,
Lorenza Marotti,
Françoise Van Hemelryck
et al.
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1392-1400
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| Basic and preclinical research |
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p63 transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation
11 July 2011
Abstract: The p53-family member, p63 is a transcription factor that influences cellular adhesion, motility, proliferation, survival and apoptosis, and has a major role in regulating epithelial stem ce...
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Linda Boldrup,
Philip J. Coates,
Göran Laurell,
Karin Nylander
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1401-1406
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Goshajinkigan reduces oxaliplatin-induced peripheral neuropathy without affecting anti-tumour efficacy in rodents
12 September 2011
Abstract: Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes acute and chronic neuropathies in patients. Goshajinkigan (GJG) is a Kampo medicine that is used for the treatm...
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Soichiro Ushio,
Nobuaki Egashira,
Hikaru Sada,
Takehiro Kawashiri,
Masafumi Shirahama,
Ken Masuguchi,
Ryozo Oishi
et al.
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1407-1413
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| Letters to the Editor |
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Reply letter to: Salvage radiotherapy: A plea for dose-escalation with intensity modulated radiotherapy
24 February 2012
We thank Dr. Ost and colleagues for acknowledging our recent article and for their thoughtful commentary. They correctly point out that since our analysis was performed, two important articles regardi...
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Nitin Ohri,
Adam P. Dicker,
Timothy N. Showalter
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1414
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Salvage radiotherapy: A plea for dose-escalation with intensity-modulated radiotherapy
24 February 2012
We would like to congratulate Ohri et al. with their recent systematic review, addressing both the timing and dose of salvage radiotherapy (SRT) for prostate cancer. Their model confirms previous repo...
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Piet Ost,
Cesare Cozzarini,
Alberto Bossi,
Gert De Meerleer
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1415-1416
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