The Journal of Molecular Diagnostics
Volume 13, Issue 5 , Pages 485-492 , September 2011

A Multiplex SNaPshot Assay as a Rapid Method for Detecting KRAS and BRAF Mutations in Advanced Colorectal Cancers

  • Sandrine Magnin

      Affiliations

    • Platform of Molecular Biology of Cancers, University Hospital of Besançon, Besançon, France
    • EA 3181, IFR 133, University of Franche-Comte, Besançon, France
  • ,
  • Erika Viel

      Affiliations

    • Services of Medical Oncology, University Hospital of Besançon, Besançon, France
  • ,
  • Alice Baraquin

      Affiliations

    • Platform of Molecular Biology of Cancers, University Hospital of Besançon, Besançon, France
  • ,
  • Severine Valmary-Degano

      Affiliations

    • EA 3181, IFR 133, University of Franche-Comte, Besançon, France
    • Services of Pathology and Cytology, University Hospital of Besançon, Besançon, France
  • ,
  • Bernadette Kantelip

      Affiliations

    • EA 3181, IFR 133, University of Franche-Comte, Besançon, France
    • Services of Pathology and Cytology, University Hospital of Besançon, Besançon, France
  • ,
  • Jean-Luc Pretet

      Affiliations

    • Platform of Molecular Biology of Cancers, University Hospital of Besançon, Besançon, France
    • EA 3181, IFR 133, University of Franche-Comte, Besançon, France
  • ,
  • Christiane Mougin

      Affiliations

    • Platform of Molecular Biology of Cancers, University Hospital of Besançon, Besançon, France
    • EA 3181, IFR 133, University of Franche-Comte, Besançon, France
  • ,
  • Marthe Bigand

      Affiliations

    • Services of Pathology and Cytology, University Hospital of Besançon, Besançon, France
  • ,
  • Benoît Girardo

      Affiliations

    • Services of Pathology and Cytology, University Hospital of Besançon, Besançon, France
  • ,
  • Christophe Borg

      Affiliations

    • Services of Medical Oncology, University Hospital of Besançon, Besançon, France
    • INSERM UMR 645, IFR 133, University of Franche-Comte, Besançon, France
    • EFS Bourgogne/Franche-Comte, Besançon, France
  • ,
  • Christophe Ferrand

      Affiliations

    • Platform of Molecular Biology of Cancers, University Hospital of Besançon, Besançon, France
    • INSERM UMR 645, IFR 133, University of Franche-Comte, Besançon, France
    • EFS Bourgogne/Franche-Comte, Besançon, France
    • Corresponding Author InformationAddress reprint requests to Christophe Ferrand, Ph.D., INSERM UMR645, EFS Bourgogne/Franche-Comte, 1 Bd Alexandre Fleming, F-25020 Besançon cedex, France

,Accepted 24 May 2011.

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 This work was supported by the Institut National du Cancer (INCa) and the University Hospital Centre of Besançon (Contrat d'Innovation 2009).

 Supplemental material for this article can be found at http://jmd.amjpathol.org or at doi: 10.1016/j.jmoldx.2011.05.010.

PII: S1525-1578(11)00181-4

doi: 10.1016/j.jmoldx.2011.05.010

The Journal of Molecular Diagnostics
Volume 13, Issue 5 , Pages 485-492 , September 2011