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Editorial
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1
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Product review
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3-4
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Protein A-Immunoadsorption in Chemotherapy Associated Hemolytic-uremic Syndrome
Abstract: Circulating IgG-immune complexes (IgG-IC) play a role in the complex etiology of C-HUS. In an ongoing open clinical study protein A immunoadsorption treatment is carried out for patients who...
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E.J Borghardt,
E.J Kirchertz,
I Marten,
K Fenchel
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5-7
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Immunological Effects of Therapeutic Immunoadsorption with Respect to Biocompatibility
Abstract: The activation of the complement system leading to generation of anaphylatoxins and the membrane attack complex depends on the chemical nature of the adsorptive system and the anticoagulatio...
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Janos G Kadar,
Marius Parusel,
Peter J Spaeth
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9-23
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Immunoglobulin and Circulating Immune Complex Kinetics During Immunoadsorption onto Protein A Sepharose
Abstract: Immunoadsorption onto protein A sepharose can be applied to eliminate immunoglobulins, autoantibodies and circulating immune complexes from the circulation. In vivo kinetic studies showed th...
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Norbert Braun,
Sylvia Gutenberger,
Christiane M Erley,
Teut Risler
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25-31
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Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Superiority of Protein A Immunoadsorption over Plasma Exchange Treatment
Abstract: We present a patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) who was treated regularly with plasma exchanges (PE) because response to other therapies including ...
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Heidrun Ullrich,
Behrouz Mansouri-Taleghani,
Karl J Lackner,
Berthold Schalke,
Ulrich Bogdahn,
Gerd Schmitz
et al.
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33-38
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Therapy of Coagulation Factor VIII Autoantibodies with Long-term Extracorporeal Protein A Adsorption and Immunosuppression
Abstract: Acquired factor VIII (FVIII) inhibitors in non-haemophiliacs may pose serious treatment problems. Materials and Methods: For IgG-adsorptions we utilized an automated plasma separation device...
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Behrouz Mansouri Taleghani,
Ralf Grossmann,
Franz Keller,
Dieter Wiebecke
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39-42
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Treatment of Severe Myasthenia Gravis with Protein A Immunoadsorption and Cyclophosphamide
Abstract: Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction caused by antibodies against the nicotinic acetylcholine receptor (AChR-Ab). We report a 16-year-old girl with s...
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Peter Flachenecker,
Behrouz Mansouri Taleghani,
Ralf Gold,
Ralf Grossmann,
Dieter Wiebecke,
Klaus Viktor Toyka
et al.
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43-46
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Protein A Immunoadsorption in Alloimmunized Patients Refractory to Platelet Transfusions and in Patients with Treatment-resistant Immune Thrombocytopoenic Purpura
Destruction of platelets by immune mechanisms is in general associated with increased levels of immunoglobulins or complement attached to the surface of platelets.Allo-/autoantibodies or drugs are dir...
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K Gutensohn,
A.R Zander,
S.D Rowley,
J Hester,
P Kuehnl
et al.
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47-52
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Protein A immunoadsorption (IA) in renal transplantation patients with vascular rejection
Abstract: Vascular rejection after renal transplantation is connected with a higher frequency of allograft dysfunction or graft loss. Plasmapheresis as an adjunctive therapy in the treatment of humora...
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H Hickstein,
G Korten,
R Bast,
D Barz,
R Templin,
J.M Schneidewind,
Ch Kittner,
H Nizze,
R Schmidt
et al.
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53-57
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Immunoadsorption—a New Therapeutic Possibility for Multiple Sclerosis?
Abstract: A 46 year old woman suffers from chronic progressive multiple sclerosis. She was diagnosed in 1993. Because of many complications seen in conservative treatment, plasma exchange was started....
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J.M Schneidewind,
R Winkler,
W Ramlow,
M Tiess,
U Hertel,
D Sehland
et al.
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59-63
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Therapeutic Immunoadsorption—its Role in Clinical Practice
Abstract: Extracorporeal immunoadsorption onto staphylococcal protein A replaces conventional plasmapheresis because its elimination efficiency is higher while less adverse reactions are seen. Experie...
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Norbert Braun,
Janos G Kadar,
Teut Risler
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65-69
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