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Description of 2 angiogenic phenotypes in clear cell renal cell carcinoma
24 May 2012
Julien Edeline, Stéphanie Mottier, Cécile Vigneau, Florence Jouan, Christophe Perrin, Selim Zerrouki, Patricia Fergelot, Jean-Jacques Patard, Nathalie Rioux-Leclercq
Summary: Angiogenesis in clear cell renal cell carcinoma has received recent focus with the development of antiangiogenic therapies. Although tumor progression is known to be correlated with intratumo...
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Involvement of pelvic inflammation–related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis
24 May 2012
Chiho Fuseya, Akiko Horiuchi, Akiko Hayashi, Akihisa Suzuki, Tsutomu Miyamoto, Takuma Hayashi, Tanri Shiozawa
Summary: Inflammation in the ovary, including ovulation and pelvic inflammatory disease, has been proposed to play a role in the pathogenesis of ovarian cancer. Endometriotic lesions trigger a local i...
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Enhanced expression of membrane transporter and drug resistance in keloid fibroblasts
23 May 2012
Nan Song, Xiaoli Wu, Zhen Gao, Guangdong Zhou, Wen Jie Zhang, Wei Liu
Summary: The mechanisms of keloid resistance to therapy and high recurrence rate remain undefined. This study explored the difference in drug resistance between keloid and normal fibroblasts. Fibrobla...
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Seminal plasma proteins in prostatic carcinoma: increased nuclear semenogelin I expression is a predictor of biochemical recurrence after radical prostatectomy
23 May 2012
Koji Izumi, Yi Li, Yichun Zheng, Jennifer Gordetsky, Jorge L. Yao, Hiroshi Miyamoto
Summary: Semenogelins and eppin are seminal plasma proteins that form a complex and inhibit sperm motility. However, the role of these proteins in prostate cancer is poorly understood. We immunohistoc...
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Neuroendocrine and mucinous differentiation in signet ring cell carcinoma of the stomach: evidence for a common cell of origin in composite tumors
21 May 2012
Naoki Kanomata
I read with interest the article by Bartley et al that described neuroendocrine and mucinous differentiation in signet ring cell carcinoma of the stomach. Their article reminded me of an old article ...
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