| |
Article Title |
Author(s) |
Type (Status) |
Available Online |
|
Description of 2 angiogenic phenotypes in clear cell renal cell carcinoma
DOI: 10.1016/j.humpath.2012.01.023
Summary: Angiogenesis in clear cell renal cell carcinoma has received recent focus with the development of antiangiogenic therapies. Although tumor progression is known to be correlated with intratumo...
|
Julien Edeline,
Stéphanie Mottier,
Cécile Vigneau,
Florence Jouan,
Christophe Perrin,
Selim Zerrouki,
Patricia Fergelot,
Jean-Jacques Patard,
Nathalie Rioux-Leclercq
et al.
|
Full-length article
(In Press Corrected Proof)
|
24 May 2012 |
|
Involvement of pelvic inflammation–related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis
DOI: 10.1016/j.humpath.2012.02.005
Summary: Inflammation in the ovary, including ovulation and pelvic inflammatory disease, has been proposed to play a role in the pathogenesis of ovarian cancer. Endometriotic lesions trigger a local i...
|
Chiho Fuseya,
Akiko Horiuchi,
Akiko Hayashi,
Akihisa Suzuki,
Tsutomu Miyamoto,
Takuma Hayashi,
Tanri Shiozawa
et al.
|
Full-length article
(In Press Corrected Proof)
|
24 May 2012 |
|
Enhanced expression of membrane transporter and drug resistance in keloid fibroblasts
DOI: 10.1016/j.humpath.2011.12.026
Summary: The mechanisms of keloid resistance to therapy and high recurrence rate remain undefined. This study explored the difference in drug resistance between keloid and normal fibroblasts. Fibrobla...
|
Nan Song,
Xiaoli Wu,
Zhen Gao,
Guangdong Zhou,
Wen Jie Zhang,
Wei Liu
et al.
|
Full-length article
(In Press Corrected Proof)
|
23 May 2012 |
|
Seminal plasma proteins in prostatic carcinoma: increased nuclear semenogelin I expression is a predictor of biochemical recurrence after radical prostatectomy
DOI: 10.1016/j.humpath.2012.02.008
Summary: Semenogelins and eppin are seminal plasma proteins that form a complex and inhibit sperm motility. However, the role of these proteins in prostate cancer is poorly understood. We immunohistoc...
|
Koji Izumi,
Yi Li,
Yichun Zheng,
Jennifer Gordetsky,
Jorge L. Yao,
Hiroshi Miyamoto
et al.
|
Full-length article
(In Press Corrected Proof)
|
23 May 2012 |
|
Neuroendocrine and mucinous differentiation in signet ring cell carcinoma of the stomach: evidence for a common cell of origin in composite tumors
DOI: 10.1016/j.humpath.2012.03.017
I read with interest the article by Bartley et al that described neuroendocrine and mucinous differentiation in signet ring cell carcinoma of the stomach. Their article reminded me of an old article ...
|
Naoki Kanomata
|
Correspondence
(In Press Corrected Proof)
|
21 May 2012 |
|
CD5(−) diffuse large B-cell lymphoma with peculiar cyclin D1 + phenotype. Pathologic and molecular characterization of a single case
DOI: 10.1016/j.humpath.2012.03.021
|
Francisco Izquierdo,
Dimas Suárez
|
Correspondence
(In Press Corrected Proof)
|
21 May 2012 |
|
GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor
DOI: 10.1016/j.humpath.2012.02.011
Summary: Although GATA binding protein 3, a zinc finger transcription factor and an estrogen receptor–regulated gene, has recently been suggested as a marker for urothelium, prognostic significance of...
|
Hiroshi Miyamoto,
Koji Izumi,
Jorge L. Yao,
Yi Li,
Qi Yang,
Loralee A. McMahon,
Nilda Gonzalez-Roibon,
David G. Hicks,
David Tacha,
George J. Netto
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 May 2012 |
|
Hyalinized stroma in clear cell carcinoma of the ovary: how is it formed?
DOI: 10.1016/j.humpath.2012.02.012
Summary: Ovarian clear cell carcinoma often shows stromal hyalinization. The main constituents of hyalinization are basement membrane materials, including laminin and type IV collagen. Although it is ...
|
Noriko Kato,
Junko Takeda,
Masayuki Fukase,
Teiichi Motoyama
|
Full-length article
(In Press Corrected Proof)
|
21 May 2012 |
|
Follicular lymphoma with prominent Dutcher body formation: a pathologic study of 3 cases in comparison with nodal or splenic lymphoplasmacytic lymphoma and marginal zone lymphoma
DOI: 10.1016/j.humpath.2012.02.009
Summary: Dutcher bodies have been described in lymphoid neoplasms with plasmacytic differentiation, including plasma cell myeloma, lymphoplasmacytic lymphoma, and marginal zone lymphoma. We report a p...
|
Endi Wang,
Maggie Stoecker,
James Burchette,
Catherine Rehder
|
Full-length article
(In Press Corrected Proof)
|
21 May 2012 |
|
Immunohistochemical and oncogenetic analyses of the esophageal basaloid squamous cell carcinoma in comparison with conventional squamous cell carcinomas
DOI: 10.1016/j.humpath.2012.02.010
Summary: Basaloid squamous cell carcinoma of the esophagus is a rare variant of squamous cell carcinoma. We reviewed 878 cases of esophageal squamous cell carcinoma and detected 22 cases (3%) of basal...
|
Abdukadir Imamhasan,
Hiroyuki Mitomi,
Tsuyoshi Saito,
Takuo Hayashi,
Michiko Takahashi,
Yoshiaki Kajiyama,
Takashi Yao
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 May 2012 |
|
Concordance between whole-slide imaging and light microscopy for routine surgical pathology
DOI: 10.1016/j.humpath.2011.12.023
Summary: The use of high-resolution digital images of histopathology slides as a routine diagnostic tool for surgical pathology was investigated. The study purpose was to determine the diagnostic conc...
|
W. Scott Campbell,
Subodh M. Lele,
William W. West,
Audrey J. Lazenby,
Lynette M. Smith,
Steven H. Hinrichs
et al.
|
Full-length article
(In Press Corrected Proof)
|
16 May 2012 |
|
Tissue-based predictors of germ-line BRCA1 mutations: implications for triaging of genetic testing
DOI: 10.1016/j.humpath.2012.02.002
Summary: BRCA testing of patients with breast cancer considered at high risk for having a germ-line BRCA mutation usually consists of comprehensive mutational analysis of both BRCA1 and BRCA2. A more ...
|
Jeannine de la Cruz,
Fabrice Andre,
Robyn K. Harrell,
Roland L. Bassett,
Banu Arun,
Marie-Christine Mathieu,
Suzette Delaloge,
Michael Z. Gilcrease
et al.
|
Full-length article
(In Press Corrected Proof)
|
16 May 2012 |
|
Abnormal expression of transcription factor activator protein-2α in pathologic placentas
DOI: 10.1016/j.humpath.2012.01.011
Summary: Recent studies from our laboratory have indicated that the transcription factor activator protein-2α plays a critical role in the differentiation of human villous cytotrophoblast cells to syn...
|
Rachel M. Sheridan,
Jerzy Stanek,
Jane Khoury,
Stuart Handwerger
|
Full-length article
(In Press Corrected Proof)
|
11 May 2012 |
|
Mammary and vaginal myofibroblastomas are genetically related lesions: fluorescence in situ hybridization analysis shows deletion of 13q14 region
DOI: 10.1016/j.humpath.2012.01.015
Summary: Partial monosomy 13q, a chromosomal alteration originally reported in spindle cell lipoma, has also been documented in a few cases of mammary myofibroblastoma. Subsequently, a monoallelic los...
|
Gaetano Magro,
Alberto Righi,
Laura Casorzo,
Torrisi Antonietta,
Lucia Salvatorelli,
Denisa Kacerovská,
Dmitry Kazakov,
Michal Michal
et al.
|
Full-length article
(In Press Corrected Proof)
|
11 May 2012 |
|
Pericytoma with t(7;12) and ACTB-GLI1 fusion arising in bone
DOI: 10.1016/j.humpath.2012.01.019
Summary: Cytogenetic analysis of a primary bone neoplasm with pericytic features in a 67-year-old man revealed a t(7;12)(p22;q13) among other karyotypic abnormalities. Subsequent molecular studies con...
|
Julia A. Bridge,
Kyle Sanders,
Dali Huang,
Marilu Nelson,
James R. Neff,
David Muirhead,
Craig Walker,
Thomas A. Seemayer,
Janos Sumegi
et al.
|
Short communication
(In Press Corrected Proof)
|
11 May 2012 |
|
False-positive and false-negative sentinel node findings in 473 breast cancers
DOI: 10.1016/j.humpath.2012.01.022
Summary: We reviewed lymph node samples from 473 consecutive breast cancer cases with either negative sentinel nodes or isolated tumor cells to evaluate the rate of false-positive sentinel node findin...
|
Leena Strien,
Marjut Leidenius,
Päivi Heikkilä
|
Full-length article
(In Press Corrected Proof)
|
11 May 2012 |
|
P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy
DOI: 10.1016/j.humpath.2012.02.003
Summary: Although pathologic response to neoadjuvant chemotherapy is highly correlated with survival among patients with osteosarcoma, there are currently no established molecular markers to predict r...
|
Dariusz Borys,
Robert J. Canter,
Benjamin Hoch,
Steve R. Martinez,
Robert M. Tamurian,
Brian Murphy,
John W. Bishop,
Andrew Horvai
et al.
|
Full-length article
(In Press Corrected Proof)
|
11 May 2012 |
|
Parenchymal-stromal switching for extracellular matrix production on invasion of oral squamous cell carcinoma
DOI: 10.1016/j.humpath.2012.02.006
Summary: It is poorly understood which cell type, tumor cells, or stromal cells are responsible for the production of extracellular matrix molecules in the neoplastic stroma. We studied the expression...
|
Hamdy Metwaly,
Satoshi Maruyama,
Manabu Yamazaki,
Masayuki Tsuneki,
Tatsuya Abé,
Kai Yu Jen,
Jun Cheng,
Takashi Saku
et al.
|
Full-length article
(In Press Corrected Proof)
|
11 May 2012 |
|
Wood dust–related mutational profile of TP53 in intestinal-type sinonasal adenocarcinoma
DOI: 10.1016/j.humpath.2012.01.016
Summary: Intestinal-type sinonasal adenocarcinoma represents 8% to 25% of all malignant sinonasal cancer and is etiologically related to occupational exposure to wood dust. Despite its clear etiology,...
|
Jhudit Pérez-Escuredo,
Jorge García Martínez,
Blanca Vivanco,
César Álvarez Marcos,
Carlos Suárez,
José Luis Llorente,
Mario A. Hermsen
et al.
|
Full-length article
(In Press Corrected Proof)
|
10 May 2012 |
|
Advances in the molecular pathobiology of B-lymphoblastic leukemia
DOI: 10.1016/j.humpath.2012.02.004
Summary: B-lymphoblastic leukemia/lymphoma, also known as B-acute lymphoblastic leukemia, is derived from B-cell progenitors. B-acute lymphoblastic leukemia occurs predominantly in children, but can o...
|
Yi Zhou,
M. James You,
Ken H. Young,
Pei Lin,
Gary Lu,
L. Jeffrey Medeiros,
Carlos E. Bueso-Ramos
et al.
|
Short communication
(In Press Corrected Proof)
|
10 May 2012 |
|
Thymomas with prominent signet ring cell–like features: a clinicopathologic and immunohistochemical study of 10 cases
DOI: 10.1016/j.humpath.2012.01.013
Summary: Ten cases of an unusual growth pattern of thymomas are presented. The patients were 8 men and 2 women between the ages of 43 and 62 years. Clinically, 6 patients presented with symptoms of ch...
|
Annikka Weissferdt,
Cesar A. Moran
|
Full-length article
(In Press Corrected Proof)
|
10 May 2012 |
|
International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems
DOI: 10.1016/j.humpath.2012.01.020
Summary: The aim of this study was to ascertain the level of concordance among gastrointestinal pathologists for regression grading in rectal cancers treated with neoadjuvant chemoradiation. Seventeen...
|
Runjan Chetty,
Pelvender Gill,
Dhirendra Govender,
Adrian Bateman,
Hee Jin Chang,
Vikram Deshpande,
David Driman,
Marisa Gomez,
Godman Greywoode,
Eleanor Jaynes,
C. Soon Lee,
Michael Locketz,
Corwyn Rowsell,
Anne Rullier,
Stefano Serra,
Neil Shepherd,
Eva Szentgyorgyi,
Rajkumar Vajpeyi,
Lai Mun Wang,
Andrew Bateman
et al.
|
Full-length article
(In Press Corrected Proof)
|
10 May 2012 |
|
Rearrangement of the ETS genes ETV-1, ETV-4, ETV-5, and ELK-4 is a clonal event during prostate cancer progression
DOI: 10.1016/j.humpath.2012.01.018
Summary: ETS gene rearrangements are frequently found in prostate cancer. Several studies have assessed the rearrangement status of the most commonly found ETS rearranged gene ERG, and the less freque...
|
Zaki Shaikhibrahim,
Martin Braun,
Pavel Nikolov,
Diana Boehm,
Veit Scheble,
Roopika Menon,
Falko Fend,
Glen Kristiansen,
Sven Perner,
Nicolas Wernert
et al.
|
Full-length article
(In Press Corrected Proof)
|
09 May 2012 |
|
Evidence for clonal fibroblast proliferation and autoimmune process in idiopathic retroperitoneal fibrosis
DOI: 10.1016/j.humpath.2012.01.012
Summary: Idiopathic retroperitoneal fibrosis is an uncommon disease characterized by encasement of retroperitoneal structures by fibrosis and chronic inflammation. Multiple etiologies have been propos...
|
Jessica A. Clevenger,
Mingsheng Wang,
Gregory T. MacLennan,
Rodolfo Montironi,
Antonio Lopez-Beltran,
Liang Cheng
et al.
|
Full-length article
(In Press Corrected Proof)
|
07 May 2012 |
|
Immunohistochemical expression of minichromosome maintenance complex protein 2 predicts biochemical recurrence in prostate cancer: a tissue microarray and digital imaging analysis–based study of 428 cases
DOI: 10.1016/j.humpath.2012.01.007
Summary: Prostate cancer remains a major health problem in the United States. Established clinicopathologic parameters such as Gleason score, T stage, and prostate-specific antigen levels are currentl...
|
Antoun Toubaji,
Siobhan Sutcliffe,
Alcides Chaux,
Kristen Lecksell,
Jessica Hicks,
Angelo M. De Marzo,
Elizabeth A. Platz,
George J. Netto
et al.
|
Full-length article
(In Press Corrected Proof)
|
04 May 2012 |
|
Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon
DOI: 10.1016/j.humpath.2012.01.005
Summary: Mucin 16 (cancer antigen 125) is a cell surface glycoprotein that plays a role in promoting cancer cell growth in ovarian cancer. The aims of this study were to examine mucin 16 expression in...
|
Mirte M. Streppel,
Audrey Vincent,
Radha Mukherjee,
Nathaniel R. Campbell,
Shih-Hsun Chen,
Konstantinos Konstantopoulos,
Michael G. Goggins,
Isabelle Van Seuningen,
Anirban Maitra,
Elizabeth A. Montgomery
et al.
|
Full-length article
(In Press Corrected Proof)
|
30 April 2012 |
|
Staining for acid-fast bacilli in surgical pathology: practice patterns and variations
DOI: 10.1016/j.humpath.2012.01.006
Summary: Analysis of acid-fast bacilli stains on sputum smears for the diagnosis of tuberculosis has a long history, but quality control for acid-fast bacilli in histologic sections is not as well est...
|
Roseann I. Wu,
Eugene J. Mark,
Jennifer L. Hunt
|
Full-length article
(In Press Corrected Proof)
|
30 April 2012 |
|
Relationship between columnar cell changes and low-grade carcinoma in situ of the breast—a cytogenetic study
DOI: 10.1016/j.humpath.2012.02.001
Summary: Columnar cell lesions of the breast include columnar cell changes without atypia and columnar cell changes with atypia. The latter frequently coexist and share molecular changes with low-grad...
|
Edna May L. Go,
Julia Y.S. Tsang,
Yun-Bi Ni,
Alex M. Yu,
Paulo Mendoza,
Siu-Ki Chan,
Christopher C. Lam,
Philip C. Lui,
Puay-Hoon Tan,
Gary M. Tse
et al.
|
Full-length article
(In Press Corrected Proof)
|
30 April 2012 |
|
Histologic grading of urothelial carcinoma: a reappraisal
DOI: 10.1016/j.humpath.2012.01.008
Summary: A uniform grading system for bladder cancer will allow for valid comparison of treatment results among different centers. The introduction of the World Health Organization (2004)/Internationa...
|
Liang Cheng,
Gregory T. MacLennan,
Antonio Lopez-Beltran
|
Short communication
(In Press Corrected Proof)
|
30 April 2012 |
|
Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas
DOI: 10.1016/j.humpath.2012.01.009
Summary: Dysregulation of the mammalian target of rapamycin and hypoxia-induced pathways has been consistently identified in clear cell renal cell carcinomas. However, experience with non–clear cell r...
|
Alcides Chaux,
Luciana Schultz,
Roula Albadine,
Jessica Hicks,
Jenny J. Kim,
Mohamad E. Allaf,
Michael A. Carducci,
Ronald Rodriguez,
Hans-Joerg Hammers,
Pedram Argani,
Victor E. Reuter,
George J. Netto
et al.
|
Full-length article
(In Press Corrected Proof)
|
30 April 2012 |
|
Genetic up-regulation and overexpression of PLEKHA7 differentiates invasive lobular carcinomas from invasive ductal carcinomas
DOI: 10.1016/j.humpath.2012.01.017
Summary: Molecular differentiation between invasive lobular carcinomas (ILCs) and invasive ductal carcinomas (IDCs) of the breast has not been well defined. We investigated gene expression differences...
|
Bàrbara Castellana,
Daniel Escuin,
Maitane Pérez-Olabarria,
Tania Vázquez,
Josefina Muñoz,
Gloria Peiró,
Agustí Barnadas,
Enrique Lerma
et al.
|
Full-length article
(In Press Corrected Proof)
|
27 April 2012 |
|
Solid pseudopapillary neoplasm, pancreas type, presenting as a primary ovarian neoplasm
DOI: 10.1016/j.humpath.2011.12.018
Summary: Solid pseudopapillary neoplasm has historically been associated with the pancreas, categorized as a tumor of low malignancy. Recently, solid pseudopapillary neoplasm was reported to arise as ...
|
Lisa M. Stoll,
Ram Parvataneni,
Michael W. Johnson,
Dorina Gui,
Oliver Dorigo,
Peggy Sullivan
et al.
|
Short communication
(In Press Corrected Proof)
|
25 April 2012 |
|
A distinctive traslocation carcinoma of the kidney; “rosette forming,” t(6;11), HMB45-positive renal tumor: a histomorphologic, immunohistochemical, ultrastructural, and molecular genetic study of 4 cases
DOI: 10.1016/j.humpath.2012.03.009
We have read the interesting article of Petersson et al in which they exhaustively study 4 cases of “rosette-forming” t( 6;11 ), HMB45-positive renal tumors, a variant of traslocation-associated carc...
|
Dimas Suárez-Vilela,
Francisco Miguel Izquierdo,
Jose Ramón Méndez-Alvarez,
Erasmo Miguélez-García,
Francisco Domínguez-Iglesias
et al.
|
Correspondence
(In Press Corrected Proof)
|
23 April 2012 |
|
Multiple coronary artery–left ventricular fistulas causing sudden death in a young woman
DOI: 10.1016/j.humpath.2011.12.025
Summary: Multiple coronary artery fistulae arising from right and left coronary arteries were found at autopsy in a 22-year-old woman, dying suddenly while playing football. This is the fifth patholog...
|
Giovanni Bartoloni,
Alexandra Giorlandino,
Antonio Maria Calafiore,
Rosario Caltabiano,
Silvio Cosentino,
Giuseppe Algieri,
Angela Pucci
et al.
|
Short communication
(In Press Corrected Proof)
|
23 April 2012 |
|
Anterior gradient 2 profiling in Barrett columnar epithelia and adenocarcinoma
DOI: 10.1016/j.humpath.2012.01.004
Summary: Barrett esophagus is the precancerous lesion leading to Barrett adenocarcinoma. The natural history of Barrett metaplasia and its neoplastic progression are still controversial. Anterior grad...
|
Marco Pizzi,
Matteo Fassan,
Stefano Realdon,
Mariangela Balistreri,
Giorgio Battaglia,
Cinzia Giacometti,
Giovanni Zaninotto,
Vittorina Zagonel,
Michele De Boni,
Massimo Rugge
et al.
|
Full-length article
(In Press Corrected Proof)
|
23 April 2012 |
|
Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection
DOI: 10.1016/j.humpath.2011.12.024
Summary: Gastroesophageal reflux disease is associated with impaired epithelial barrier function and abnormal expression of proteins forming cell-cell contacts by tight junctions and desmosomes in dis...
|
Thomas Wex,
Doerthe Kuester,
Klaus Mönkemüller,
Antje Stahr,
Lucia C. Fry,
Arne Kandulski,
Siegfried Kropf,
Albert Roessner,
Peter Malfertheiner
et al.
|
Full-length article
(In Press Corrected Proof)
|
23 April 2012 |
|
Splenic B-cell lymphomas with more than 55% prolymphocytes in blood: evidence for prolymphocytoid transformation
DOI: 10.1016/j.humpath.2012.01.003
Summary: We describe 4 patients aged 62 to 79 years with splenomegaly and bone marrow involvement by splenic B-cell lymphoma who developed more than 55% prolymphocytes in blood. The diagnosis of B-cel...
|
Daniela Hoehn,
Roberto N. Miranda,
Rashmi Kanagal-Shamanna,
Pei Lin,
L. Jeffrey Medeiros
et al.
|
Full-length article
(In Press Corrected Proof)
|
20 April 2012 |
|
Immunohistochemical analysis of polycomb group protein expression in advanced gastric cancer
DOI: 10.1016/j.humpath.2011.12.019
Summary: The polycomb group proteins have recently captured the attention of cancer biologists. enhancer of zeste homologue 2 (EZH2) and B lymphoma Mo-MLV insertion region 1 homolog (BMI-1) are the be...
|
Hyunjoo Lee,
Sun Och Yoon,
Woon Yong Jeong,
Han Kyeom Kim,
Aeree Kim,
Baek-hui Kim
et al.
|
Full-length article
(In Press Corrected Proof)
|
20 April 2012 |
|
Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers
DOI: 10.1016/j.humpath.2011.12.022
Summary: DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was design...
|
Riadh Ben Gacem,
Mohamed Hachana,
Sonia Ziadi,
Soumaya Ben Abdelkarim,
Samir Hidar,
Mounir Trimeche
et al.
|
Full-length article
(In Press Corrected Proof)
|
20 April 2012 |
|
Signal transduction pathway analysis in fibromatosis: receptor and nonreceptor tyrosine kinases
DOI: 10.1016/j.humpath.2011.12.021
Summary: Despite reports of receptor tyrosine kinase activation in desmoid-type fibromatosis, therapeutic benefits of kinase inhibitor therapy are unpredictable. Variability in signal transduction or ...
|
Justin M.M. Cates,
Jennifer O. Black,
Doha M. Itani,
John H. Fasig,
Vicki L. Keedy,
Kenneth R. Hande,
Brent W. Whited,
Kelly C. Homlar,
Jennifer L. Halpern,
Ginger E. Holt,
Herbert S. Schwartz,
Cheryl M. Coffin
et al.
|
Full-length article
(In Press Corrected Proof)
|
20 April 2012 |
|
A review of adenoid cystic carcinoma of the breast with emphasis on its molecular and genetic characteristics
DOI: 10.1016/j.humpath.2012.01.002
Summary: Breast carcinomas that do not express estrogen receptor α, progesterone receptor, or human epidermal growth factor receptor 2 are frequently grouped together as “triple negative” and consider...
|
Semir Vranic,
Richard Bender,
Juan Palazzo,
Zoran Gatalica
|
Short communication
(In Press Corrected Proof)
|
20 April 2012 |
|
Combined metallothioneins and p53 proteins expression as a prognostic marker in patients with Dukes stage B and C colorectal cancer
DOI: 10.1016/j.humpath.2011.12.014
Summary: Our study aimed to evaluate metallothionein and p53 expression in colorectal cancer and to correlate their combined expression with selected clinical and pathologic variables of the disease, ...
|
J.M. Arriaga,
I.A. Bravo,
L. Bruno,
S. Morales Bayo,
A. Hannois,
F. Sanchez Loria,
F. Pairola,
E. Huertas,
M.P. Roberti,
Y.S. Rocca,
M. Aris,
M.M. Barrio,
S. Baffa Trasci,
E.M. Levy,
J. Mordoh,
M. Bianchini
et al.
|
Full-length article
(In Press Corrected Proof)
|
19 April 2012 |
|
Unusual DNA mismatch repair–deficient tumors in Lynch syndrome: a report of new cases and review of the literature
DOI: 10.1016/j.humpath.2011.12.012
Summary: Immunohistochemical detection of DNA mismatch repair proteins and polymerase chain reaction detection of microsatellite instability have enhanced the recognition of mismatch repair–deficient ...
|
Yevgeniy Karamurzin,
Zhaoshi Zeng,
Zsofia K. Stadler,
Liying Zhang,
Ihsane Ouansafi,
Hikmat A. Al-Ahmadie,
Christine Sempoux,
Leonard B. Saltz,
Robert A. Soslow,
Eileen M. O'Reilly,
Philip B. Paty,
Daniel G. Coit,
Jinru Shia,
David S. Klimstra
et al.
|
Full-length article
(In Press Corrected Proof)
|
19 April 2012 |
|
Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer
DOI: 10.1016/j.humpath.2011.12.013
Summary: Neoadjuvant chemotherapy or preoperative systemic therapy is increasingly considered for patients with operable breast cancer. Patients with breast cancer were examined for pathologic factors...
|
Rin Yamaguchi,
Maki Tanaka,
Ayako Yano,
Gary M. Tse,
Miki Yamaguchi,
Keiko Koura,
Naoki Kanomata,
Atsushi Kawaguchi,
Jun Akiba,
Yoshiki Naito,
Koichi Ohshima,
Hirohisa Yano
et al.
|
Full-length article
(In Press Corrected Proof)
|
19 April 2012 |
|
α-Fetoprotein–producing gastric carcinoma and combined hepatocellular and cholangiocarcinoma show similar morphology but different histogenesis with respect to SALL4 expression
DOI: 10.1016/j.humpath.2011.11.022
Summary: α-Fetoprotein is expressed in hepatocellular carcinoma, yolk sac tumor, and some gastric carcinomas. The α-fetoprotein–producing gastric carcinoma composed of hepatoid and common adenocarcino...
|
Hiroko Ikeda,
Yasunori Sato,
Norihide Yoneda,
Kenichi Harada,
Motoko Sasaki,
Seiko Kitamura,
Yoshiko Sudo,
Akishi Ooi,
Yasuni Nakanuma
et al.
|
Full-length article
(In Press Corrected Proof)
|
19 April 2012 |
|
Differential loss of heterozygosity profile on chromosome 3p in ductal and lobular breast carcinomas
DOI: 10.1016/j.humpath.2011.12.008
Summary: The 2 main histologic types of infiltrating breast cancer, invasive lobular and invasive ductal carcinoma, are morphologically and clinically distinct. Studies revealed that different pattern...
|
Márcia Maria Costa de Oliveira,
Sarah Franco Vieira de Oliveira,
Rubens Silveira Lima,
Cícero de Andrade Urban,
Luciane Regina Cavalli,
Enilze Maria de Souza Fonseca Ribeiro,
Iglenir João Cavalli
et al.
|
Full-length article
(In Press Corrected Proof)
|
16 April 2012 |
|
A cytogenetic analysis of 2 cases of phosphaturic mesenchymal tumor of mixed connective tissue type
DOI: 10.1016/j.humpath.2011.11.020
Summary: Phosphaturic mesenchymal tumor of mixed connective tissue type is a rare, histologically distinctive mesenchymal neoplasm associated with tumor-induced osteomalacia resulting from production ...
|
Rondell P. Graham,
Andrew L. Folpe,
Andre M. Oliveira,
Kevin J. Meyer,
Robert B. Jenkins,
Franklin H. Sim,
William R. Sukov
et al.
|
Short communication
(In Press Corrected Proof)
|
13 April 2012 |
|
Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma
DOI: 10.1016/j.humpath.2011.12.007
Summary: Somatic mutations in isocitrate dehydrogenase 1 and 2 genes are common in gliomas and help stratify patients with brain cancer into histologic and molecular subtypes. However, these mutations...
|
Benjamin R. Kipp,
Jesse S. Voss,
Sarah E. Kerr,
Emily G. Barr Fritcher,
Rondell P. Graham,
Lizhi Zhang,
W. Edward Highsmith,
Jun Zhang,
Lewis R. Roberts,
Gregory J. Gores,
Kevin C. Halling
et al.
|
Full-length article
(In Press Corrected Proof)
|
13 April 2012 |
|
Oncofetal protein IMP3: a useful diagnostic biomarker for leiomyosarcoma
DOI: 10.1016/j.humpath.2011.12.020
Summary: An accurate diagnosis between leiomyoma and leiomyosarcoma is essential for patient management. IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding protein (IMP) family t...
|
Kristine Cornejo,
Min Shi,
Zhong Jiang
|
Full-length article
(In Press Corrected Proof)
|
12 April 2012 |
|
Infant brain tumors: a neuropathologic population-based institutional reappraisal
DOI: 10.1016/j.humpath.2011.12.011
Summary: The factors that impact the long-term functional outcome for infants with brain tumor are unclear. The clinicopathologic features of all infant brain tumors occurring at our institution (1982...
|
Christopher Dunham,
Shibu Pillai,
Paul Steinbok
|
Full-length article
(In Press Corrected Proof)
|
12 April 2012 |
|
Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin–binding phosphoprotein 50 in cholangiocarcinoma
DOI: 10.1016/j.humpath.2011.11.021
Summary: We performed a comparative proteomic analysis of protein expression profiles in 4 cholangiocarcinoma cell lines: K100, M156, M213, and M139. The H69 biliary cell line was used as a control. P...
|
Ponlapat Yonglitthipagon,
Chawalit Pairojkul,
Yaovalux Chamgramol,
Alex Loukas,
Jason Mulvenna,
Jeffrey Bethony,
Vajarabhongsa Bhudhisawasdi,
Banchob Sripa
et al.
|
Full-length article
(In Press Corrected Proof)
|
26 March 2012 |
|
A classification tree approach for pituitary adenomas
DOI: 10.1016/j.humpath.2011.12.003
Summary: It is difficult to evaluate the recurrence and progression potential of pituitary adenomas at presentation. The World Health Organization classification of endocrine tumors suggests that inva...
|
Alberto Righi,
Patrizia Agati,
Andrea Sisto,
Giorgio Frank,
Marco Faustini-Fustini,
Raffaele Agati,
Diego Mazzatenta,
Anna Farnedi,
Federico Menetti,
Gianluca Marucci,
Maria P. Foschini
et al.
|
Full-length article
(In Press Corrected Proof)
|
26 March 2012 |
|
Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma
DOI: 10.1016/j.humpath.2011.12.002
Summary: Fibroblast growth factor receptor 2 is a member of receptor tyrosine kinase family, and fibroblast growth factor receptor 2 gene amplification or missense mutation has been observed in variou...
|
Eun-Jung Jung,
Eun-Ji Jung,
Sun Young Min,
Min A Kim,
Woo Ho Kim
et al.
|
Full-length article
(In Press Corrected Proof)
|
22 March 2012 |
|
Correlation between tumor suppressor inhibitor of growth family member 4 expression and microvessel density in breast cancer
DOI: 10.1016/j.humpath.2011.11.018
Summary: Suppression of cell spreading and migration by inhibitor of growth 4 suggests that its loss may induce metastasis. Inhibitor of growth 4 expression level in 60 breast cancer tissues, 30 norma...
|
Liangyu Zhang,
Yingchao Wang,
Fang Zhang,
Yingwei Wang,
Qingyuan Zhang
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
Clinical and biological relevance of enhancer of zeste homolog 2 in triple-negative breast cancer
DOI: 10.1016/j.humpath.2011.12.004
Summary: The polycomb group protein, enhancer of zeste homolog 2, is a transcriptional repressor involved in cell cycle regulation and has been linked to aggressive breast cancer. We examined the clin...
|
Yaser R. Hussein,
Anil K. Sood,
Sudeshna Bandyopadhyay,
Bassam Albashiti,
Assaad Semaan,
Zeina Nahleh,
Juwon Roh,
Hee Dong Han,
Gabriel Lopez-Berestein,
Rouba Ali-Fehmi
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
The significance of plasma cell infiltrate in acute cellular rejection of liver allografts
DOI: 10.1016/j.humpath.2011.12.005
Summary: Acute cellular rejections of higher grades of histologic severity are associated with increased risk of graft failure and death after liver transplantation. Plasma cell–rich infiltrates are a...
|
Jacob Alexander,
Wenjiang Chu,
Paul E. Swanson,
Matthew M. Yeh
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
“Piling up” clear cells in müllerian-type mucinous and mixed cell–type borderline tumor do not represent concomitant clear cell neoplasms
DOI: 10.1016/j.humpath.2011.11.019
Summary: The nature of “piling up” proliferation of clear cells in müllerian mucinous/mixed borderline tumor has not been well characterized. The purpose of this study was to clarify whether or not su...
|
Yoshihiro Ohishi,
Shuichi Kurihara,
Murasaki Aman,
Tadahisa Takeuchi,
Hiroko Imamura,
Tsunehisa Kaku,
Hiroaki Kobayashi,
Norio Wake,
Yoshinao Oda
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies
DOI: 10.1016/j.humpath.2011.12.001
Summary: Hepatocellular carcinoma and intrahepatic cholangiocarcinoma account for 95% of primary liver cancer. For each of these malignancies, the outcome is dismal; incidence is rapidly increasing, a...
|
Haibo Bai,
Mariana F. Gayyed,
Dora M. Lam-Himlin,
Alison P. Klein,
Suresh K. Nayar,
Yang Xu,
Mehtab Khan,
Pedram Argani,
Duojia Pan,
Robert A. Anders
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
Carbonic anhydrase IX up-regulation is associated with adverse clinicopathologic and biologic factors in neuroblastomas
DOI: 10.1016/j.humpath.2011.12.006
Summary: The overexpression of carbonic anhydrase IX, a hypoxia-induced enzyme, is associated with an adverse prognosis in many cancers. However, carbonic anhydrase IX expression in neuroblastoma, the...
|
Josiah V. Dungwa,
Linda P. Hunt,
Pramila Ramani
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |
|
Immune receptors and adhesion molecules in human pulmonary leptospirosis
DOI: 10.1016/j.humpath.2011.11.017
Summary: Pulmonary involvement in leptospirosis has been increasingly reported in the last 20 years, being related to the severity and mortality of the disease. The pathogenesis of pulmonary hemorrhag...
|
Fabiola Del Carlo Bernardi,
Bruno Ctenas,
Luiz Fernando Ferraz da Silva,
Antonio Carlos Nicodemo,
Paulo Hilário Nascimento Saldiva,
Marisa Dolhnikoff,
Thais Mauad
et al.
|
Full-length article
(In Press Corrected Proof)
|
21 March 2012 |