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Cover 1 page OFC Full-Text PDF (827 KB)
A Brief Overview of This Month's JACI pages 1A-2A Full-Text PDF (43 KB)
Table of Contents pages 3A-13A Full-Text PDF (1022 KB)
Editorial Board page 14A Full Text | Full-Text PDF (43 KB)
Reader services
Information for Readers page 16A Full Text | Full-Text PDF (53 KB)
Footnotes1 pages 18A-20A Full Text | Full-Text PDF (488 KB)
CME Activities Calendar pages 23A-24A Full Text | Full-Text PDF (151 KB)
News beyond our pages
News Beyond Our Pages Marc E. Rothenberg, Harold S. Nelson pages 871-872 Full Text | Full-Text PDF (326 KB)
Reviews and feature articles
Clinical reviews in allergy and immunology
Management of chronic obstructive pulmonary disease: Moving beyond the asthma algorithm Erin Gordon, Stephen C. Lazarus pages 873-880 Abstract | Full Text | Full-Text PDF (152 KB)
Continuing Medical Education examination
Management of chronic obstructive pulmonary disease: Moving beyond the asthma algorithm pages 881-882 Full-Text PDF (47 KB)
Mechanisms of allergic diseases
The irreversible component of persistent asthma Rodolfo M. Pascual, Stephen P. Peters pages 883-890 Abstract | Full Text | Full-Text PDF (148 KB)
The irreversible component of persistent asthma pages 891-892 Full-Text PDF (43 KB)
The Editors' choice
The Editors' Choice Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI pages 893-894 Full Text | Full-Text PDF (251 KB)
Asthma and lower airway disease
Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study, 08 October 2009 Tmirah Haselkorn, James E. Fish, Robert S. Zeiger, Stanley J. Szefler, Dave P. Miller, Bradley E. Chipps, F. Estelle R. Simons, Scott T. Weiss, Sally E. Wenzel, Larry Borish, Eugene R. Bleecker, TENOR Study Group pages 895-902.e4 Abstract | Full Text | Full-Text PDF (360 KB)
Predicting the long-term prognosis of children with symptoms suggestive of asthma at preschool age, 10 August 2009 Daan Caudri, Alet Wijga, C. Maarten A. Schipper, Maarten Hoekstra, Dirkje S. Postma, Gerard H. Koppelman, Bert Brunekreef, Henriette A. Smit, Johan C. de Jongste pages 903-910.e7 Abstract | Full Text | Full-Text PDF (530 KB)
Celebrating JACI's 80th Anniversary-Harry L. Alexander, Editor page 910 Full-Text PDF (66 KB)
Editorial
Predicting the long-term outcome of preschool wheeze: Are we there yet? Graham Roberts pages 911-912 Full Text | Full-Text PDF (49 KB)
Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack Yukinori Enomoto, Kanami Orihara, Tetsuya Takamasu, Akio Matsuda, Yasuhiro Gon, Hirohisa Saito, Chisei Ra, Yoshimichi Okayama pages 913-920.e7 Abstract | Full Text | Full-Text PDF (961 KB)
Celebrating JACI's 80th Anniversary-Warren T. Vaughan, Associate Editor page 920 Full-Text PDF (424 KB)
Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma Tmirah Haselkorn, Robert S. Zeiger, Bradley E. Chipps, David R. Mink, Stanley J. Szefler, F. Estelle R. Simons, Marc Massanari, James E. Fish pages 921-927 Abstract | Full Text | Full-Text PDF (332 KB)
Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study, 10 August 2009 Asger Sverrild, Celeste Porsbjerg, Simon Francis Thomsen, Vibeke Backer pages 928-932.e1 Abstract | Full Text | Full-Text PDF (177 KB)
Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness, 10 August 2009 Rainer V. Haberberger, Christoph Tabeling, Sue Runciman, Birgitt Gutbier, Peter König, Manfred Andratsch, Hartwig Schütte, Norbert Suttorp, Ian Gibbins, Martin Witzenrath pages 933-941.e9 Abstract | Full Text | Full-Text PDF (2945 KB)
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis, 14 September 2009 George Philip, Janet van Adelsberg, Thomas Loeys, Nancy Liu, Peggy Wong, Eseng Lai, S. Balachandra Dass, Theodore F. Reiss pages 942-948.e9 Abstract | Full Text | Full-Text PDF (252 KB)
Celebrating JACI's 80th Anniversary-Albert H. Rowe, Editorial Board Member page 948 Full-Text PDF (113 KB)
Fractional exhaled nitric oxide measurements are most closely associated with allergic sensitization in school-age children, 14 September 2009 Daniel J. Jackson, Christine M. Virnig, Ronald E. Gangnon, Michael D. Evans, Kathy A. Roberg, Elizabeth L. Anderson, Ryan M. Burton, Lisa P. Salazar, Douglas F. DaSilva, Kathleen M. Shanovich, Christopher J. Tisler, James E. Gern, Robert F. Lemanske pages 949-953 Abstract | Full Text | Full-Text PDF (138 KB)
Maternal interpersonal trauma and cord blood IgE levels in an inner-city cohort: A life-course perspective, 14 September 2009 Michelle Judith Sternthal, Michelle Bosquet Enlow, Sheldon Cohen, Marina Jacobson Canner, John Staudenmayer, Kathy Tsang, Rosalind J. Wright pages 954-960 Abstract | Full Text | Full-Text PDF (132 KB)
Process quality measures and asthma exacerbations in the Medicaid population, 14 September 2009 Pierre L. Yong, Rachel M. Werner pages 961-966 Abstract | Full Text | Full-Text PDF (242 KB)
Celebrating JACI's 80th Anniversary-Arthur F. Coca, Editorial Board Member page 966 Full-Text PDF (76 KB)
Novel relationship of serum cholesterol with asthma and wheeze in the United States, 05 October 2009 Michael B. Fessler, Mark W. Massing, Brian Spruell, Renee Jaramillo, David W. Draper, Jennifer H. Madenspacher, Samuel J. Arbes, Agustin Calatroni, Darryl C. Zeldin pages 967-974.e15 Abstract | Full Text | Full-Text PDF (377 KB)
Celebrating JACI's 80th Anniversary-Alfred H. W. Caulfeild, Editorial Board Member page 974 Full-Text PDF (92 KB)
Long-term pathologic consequences of acute irritant-induced asthma Naoya Takeda, Karim Maghni, Sylvie Daigle, Jocelyne L'Archevêque, Lucero Castellanos, Wisam Al-Ramli, Jean-Luc Malo, Qutayba Hamid pages 975-981.e1 Abstract | Full Text | Full-Text PDF (626 KB)
Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III Sunia Foliaki, Neil Pearce, Bengt Björkstén, Javier Mallol, Stephen Montefort, Erika von Mutius, International Study of Asthma and Allergies in Childhood Phase III Study Group pages 982-989 Abstract | Full Text | Full-Text PDF (168 KB)
Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma Anne M. Fitzpatrick, Lou Ann S. Brown, Fernando Holguin, W. Gerald Teague, National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program pages 990-996.e9 Abstract | Full Text | Full-Text PDF (457 KB)
Celebrating JACI's 80th Anniversary-Francis M. Rackemann, Editorial Board Member page 996 Full-Text PDF (111 KB)
Rhinitis, sinusitis, and upper airway disease
Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy, 07 September 2009 Gabriela Senti, Nicole Graf, Susanne Haug, Nadine Rüedi, Seraina von Moos, Theodor Sonderegger, Pål Johansen, Thomas M. Kündig pages 997-1002 Abstract | Full Text | Full-Text PDF (264 KB)
Epicutaneous allergen administration: A novel approach for allergen-specific immunotherapy? Thomas Werfel pages 1003-1004 Full Text | Full-Text PDF (53 KB)
Nasal inflammatory mediators and specific IgE production after nasal challenge with grass pollen in local allergic rhinitis, 05 October 2009 Carmen Rondón, Javier Fernández, Soledad López, Paloma Campo, Inmaculada Doña, Maria J. Torres, Cristobalina Mayorga, Miguel Blanca pages 1005-1011.e1 Abstract | Full Text | Full-Text PDF (598 KB)
Rhinitis with negative skin tests and absent serum allergen-specific IgE: More evidence for local IgE? Louisa K. James, Stephen R. Durham pages 1012-1013 Full Text | Full-Text PDF (52 KB)
Targeting Ca2+ release–activated Ca2+ channel channels and leukotriene receptors provides a novel combination strategy for treating nasal polyposis Joseph Di Capite, Charmaine Nelson, Grant Bates, Anant B. Parekh pages 1014-1021.e3 Abstract | Full Text | Full-Text PDF (1328 KB)
Atopic dermatitis and skin disease
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes Lisa C. Zaba, Mayte Suárez-Fariñas, Judilyn Fuentes-Duculan, Kristine E. Nograles, Emma Guttman-Yassky, Irma Cardinale, Michelle A. Lowes, James G. Krueger pages 1022-1030.e395 Abstract | Full Text | Full-Text PDF (4407 KB)
Gestational diabetes, atopic dermatitis, and allergen sensitization in early childhood, 07 September 2009 Rajesh Kumar, Fengxiu Ouyang, Rachel E. Story, Jacqueline A. Pongracic, Xiumei Hong, Guoying Wang, Colleen Pearson, Kathryn Ortiz, Howard Bauchner, Xiaobin Wang pages 1031-1038.e4 Abstract | Full Text | Full-Text PDF (262 KB)
Correction
Correction page 1038 Full Text | Full-Text PDF (40 KB)
Food, drug, insect sting allergy, and anaphylaxis
Maternal peanut exposure during pregnancy and lactation reduces peanut allergy risk in offspring Iván López-Expósito, Ying Song, Kirsi M. Järvinen, Kamal Srivastava, Xiu-Min Li pages 1039-1046 Abstract | Full Text | Full-Text PDF (680 KB)
Predictors of severe systemic anaphylactic reactions in patients with Hymenoptera venom allergy: Importance of baseline serum tryptase—a study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity Franziska Ruëff, Bernhard Przybilla, Maria Beatrice Biló, Ulrich Müller, Fabian Scheipl, Werner Aberer, Joëlle Birnbaum, Anna Bodzenta-Lukaszyk, Floriano Bonifazi, Christoph Bucher, Paolo Campi, Ulf Darsow, Cornelia Egger, Gabrielle Haeberli, Thomas Hawranek, Michael Körner, Iwona Kucharewicz, Helmut Küchenhoff, Roland Lang, Oliviero Quercia, Norbert Reider, Maurizio Severino, Michael Sticherling, Gunter Johannes Sturm, Brunello Wüthrich pages 1047-1054 Abstract | Full Text | Full-Text PDF (381 KB)
Identification of crab proteins that elicit IgE reactivity in snow crab–processing workers, 10 August 2009 Beth V. Gill, Timothy R. Rice, André Cartier, Denise Gautrin, Barbara Neis, Lise Horth-Susin, Michael Jong, Mark Swanson, Samuel B. Lehrer pages 1055-1061 Abstract | Full Text | Full-Text PDF (837 KB)
Immune deficiencies, infection, and systemic immune disorders
Outcomes of patients with severe combined immunodeficiency treated with hematopoietic stem cell transplantation with and without preconditioning Niraj C. Patel, Javier Chinen, Howard M. Rosenblatt, I. Celine Hanson, Robert A. Krance, Mary E. Paul, Stuart L. Abramson, Lenora M. Noroski, Carla M. Davis, Filiz O. Seeborg, Samuel B. Foster, Kathryn S. Leung, Betty S. Brown, Jerome Ritz, William T. Shearer pages 1062-1069.e4 Abstract | Full Text | Full-Text PDF (457 KB)
Mechanisms of allergy and clinical immunology
Immunize and disappear—Safety-optimized mRNA vaccination with a panel of 29 allergens, 10 August 2009 Elisabeth Roesler, Richard Weiss, Esther E. Weinberger, Angelika Fruehwirth, Angelika Stoecklinger, Sven Mostböck, Fatima Ferreira, Josef Thalhamer, Sandra Scheiblhofer pages 1070-1077.e11 Abstract | Full Text | Full-Text PDF (1795 KB)
Parental characteristics, somatic fetal growth, and season of birth influence innate and adaptive cord blood cytokine responses Diane R. Gold, Gordon R. Bloomberg, William W. Cruikshank, Cynthia M. Visness, John Schwarz, Meyer Kattan, George T. O'Connor, Robert A. Wood, Melissa S. Burger, Rosalind J. Wright, Frank Witter, Aviva Lee-Parritz, Rhoda Sperling, Yoel Sadovsky, Alkis Togias, James E. Gern pages 1078-1087 Abstract | Full Text | Full-Text PDF (781 KB)
Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis Laurie E. Lenox, Taku Kambayashi, Mariko Okumura, Christopher Prieto, Karsten Sauer, Ralph M. Bunte, Martha S. Jordan, Gary A. Koretzky, Kim E. Nichols pages 1088-1098 Abstract | Full Text | Full-Text PDF (1512 KB)
Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations, 14 September 2009 Neil N. Trivedi, Bani Tamraz, Catherine Chu, Pui-Yan Kwok, George H. Caughey pages 1099-1105.e4 Abstract | Full Text | Full-Text PDF (1276 KB)
Letters to the Editor
Comparison of asthma exacerbations in pediatric and adult patients with severe or difficult-to-treat asthma, 05 October 2009 Robert S. Zeiger, Bradley E. Chipps, Tmirah Haselkorn, Lawrence Rasouliyan, F. Estelle R. Simons, James E. Fish pages 1106-1108 Full Text | Full-Text PDF (97 KB)
Bovine and porcine gelatin sensitivity in children sensitized to milk and meat, 10 August 2009 Jelena Bogdanovic, Neal A. Halsey, Robert A. Wood, Robert G. Hamilton pages 1108-1110 Full Text | Full-Text PDF (257 KB)
Hydroxyurea in the treatment of Churg-Strauss syndrome, 25 August 2009 Rachel U. Lee, Donald D. Stevenson pages 1110-1111 Full Text | Full-Text PDF (248 KB)
Idiopathic systemic capillary leak syndrome: Novel therapy for acute attacks, 25 August 2009 Amy M. Dowden, Ornella J. Rullo, Najib Aziz, Mary Beth Fasano, Talal Chatila, Zuhair K. Ballas pages 1111-1113 Full Text | Full-Text PDF (199 KB)
Peeling off the layers: Skin taping and a novel proteomics approach to study atopic dermatitis, 14 September 2009 Carolyn J. Broccardo, Spencer B. Mahaffey, Matthew Strand, Nichole A. Reisdorph, Donald Y.M. Leung pages 1113-1115.e11 Full Text | Full-Text PDF (329 KB)
Predicting outcome of repeat milk, egg, or peanut oral food challenges Kim Mudd, Melissa Paterakis, Jean Curtin-Brosnan, Elizabeth Matsui, Robert Wood pages 1115-1116 Full Text | Full-Text PDF (81 KB)
Altered epigenetic regulation and increasing severity of bronchial hyperresponsiveness in atopic asthmatic children Ruey-Chyi Su, Allan B. Becker, Anita L. Kozyrskyj, Kent T. HayGlass pages 1116-1118 Full Text | Full-Text PDF (104 KB)
Correspondence
Overweight: No association with asthma or bronchial reactivity in children, 25 August 2009 Mari Hyvärinen, Virpi Sidorof, Matti Korppi page 1119 Full Text | Full-Text PDF (50 KB)
Reply, 25 August 2009 Salome Scholtens, Alet H. Wijga, Bert Brunekreef, Henriette A. Smit pages 1119-1120 Full Text | Full-Text PDF (67 KB)
Adjustment for baseline value in the analysis of change in FEV1 over time, 14 September 2009 Alessandro Marcon, Simone Accordini, Roberto de Marco page 1120 Full Text | Full-Text PDF (56 KB)
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