| Continuing Medical Education |
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Human papillomavirus–related genital disease in the immunocompromised host: Part I
Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised ...
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Rachel H. Gormley,
Carrie L. Kovarik
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867.e1-867.e14
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CME examination
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881
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Answers to CME examination
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882
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American Board of Dermatology Examination Dates
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882
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Human papillomavirus–related genital disease in the immunocompromised host: Part II
Human papillomavirus is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. The immunocompromised population is at particular risk because of a hi...
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Rachel H. Gormley,
Carrie L. Kovarik
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883.e1-883.e17
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Answers to CME examination
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899
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CME examination
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900
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| Original Articles |
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Author(s) |
Pages |
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Molecular profiling and gene expression analysis in cutaneous sarcoidosis: The role of interleukin-12, interleukin-23, and the T-helper 17 pathway
19 September 2011
Background: Cutaneous sarcoidosis (CS) skin provides relatively noninvasive access to granulomatous sarcoidosis tissue. Objective: We sought to explore the role of the T-helper (Th)1 and Th17 pathways...
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Marc A. Judson,
Richard M. Marchell,
MaryAnn Mascelli,
Alexa Piantone,
Elliot S. Barnathan,
Kevin J. Petty,
Dion Chen,
Hongtao Fan,
Heidi Grund,
Keying Ma,
Frédéric Baribaud,
Carrie Brodmerkel
et al.
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901-910.e2
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HLA antigen expression in melanocytic lesions: Is acquisition of HLA antigen expression a biomarker of atypical (dysplastic) melanocytes?
26 March 2012
Background: Although criteria are established for the histologic diagnosis of atypical nevi (AN), consensus about the criteria in the diagnosis of and in the definition of AN is limited. Moreover, int...
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Michael Campoli,
James E. Fitzpatrick,
Whitney High,
Soldano Ferrone
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911-916.e8
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Integrating clinical/dermatoscopic findings and fluorescence in situ hybridization in diagnosing melanocytic neoplasms with less than definitive histopathologic features
03 October 2011
Background: Early diagnosis of melanoma remains of paramount importance, because it has been widely demonstrated that survival is strongly related to Breslow thickness. Several studies have shown that...
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Beatrice Nardone,
Mary Martini,
Klaus Busam,
Ashfaq Marghoob,
Dennis P. West,
Pedram Gerami
et al.
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917-922
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Dermatoscopic vascular patterns in cutaneous Merkel cell carcinoma
07 October 2011
Background: Merkel cell carcinoma (MCC) is one of the most aggressive primary cutaneous malignancies. The clinical diagnosis of MCC is often delayed. Although the rarity of this skin cancer partially ...
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Mandy S. Harting,
Mathew W. Ludgate,
Douglas R. Fullen,
Timothy M. Johnson,
Christopher K. Bichakjian
et al.
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923-927
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In search of prognostic indicators for lymphomatoid papulosis: A retrospective study of 123 patients
10 October 2011
Background: Lymphomatoid papulosis (LyP) is a benign recurrent papulonodular skin eruption with histologically malignant features that sometimes (10%-20%) progresses to lymphoma. Objective: We retrosp...
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Aieska de Souza,
Rokea A. el-Azhary,
Michael J. Camilleri,
David A. Wada,
David L. Appert,
Lawrence E. Gibson
et al.
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928-937
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Change of Address
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937
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Children’s sun exposure and sun protection: Prevalence in Australia and related parental factors
05 September 2011
Background: Reducing childhood exposure to ultraviolet radiation is important to minimize lifetime skin cancer risk. Objectives: We sought to describe the prevalence of children’s sun-related behavior...
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Suzanne Dobbinson,
Melanie Wakefield,
David Hill,
Afaf Girgis,
Joanne F. Aitken,
Kerri Beckmann,
Anthony I. Reeder,
Natalie Herd,
Matthew J. Spittal,
Andrew Fairthorne,
Kelly-Ann Bowles
et al.
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938-947
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Patient-centered online management of psoriasis: A randomized controlled equivalency trial
05 September 2011
Background: Previous research suggests that technology-enabled health care delivery may improve access to dermatologic specialty care. Outcomes research using validated outcomes measures is necessary ...
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Cindy J. Chambers,
Kory K. Parsi,
Clayton Schupp,
April W. Armstrong
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948-953
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Childhood- and later-onset vitiligo have diverse epidemiologic and clinical characteristics
10 October 2011
Background: Vitiligo onset during childhood is common. There are limited data regarding childhood-onset vitiligo. Objective: We sought to provide an epidemiologic and clinical comparison between child...
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Electra Nicolaidou,
Christina Antoniou,
Alexandra Miniati,
Eirini Lagogianni,
Athina Matekovits,
Alex Stratigos,
Andreas Katsambas
et al.
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954-958
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Fibroblastic rheumatism: A report of 4 cases with potential therapeutic implications
10 October 2011
Background: Fibroblastic rheumatism is a rare dermatoarthropathy characterized by the sudden onset of cutaneous nodules, flexion contractures, and polyarthritis. Histopathology in the correct clinical...
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Sara A. Jurado,
G.K. Glen Alvin,
M. Angelica Selim,
Clare A. Pipkin,
Douglas Kress,
Maria Jasmin J. Jamora,
Steven D. Billings
et al.
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959-965
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Expression of innate defense antimicrobial peptides in hidradenitis suppurativa
10 October 2011
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of apocrine gland-bearing skin. It is associated with alterations in innate immunity and frequent bacterial infections. Obj...
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Silke C. Hofmann,
Viola Saborowski,
Sylke Lange,
Winfried V. Kern,
Leena Bruckner-Tuderman,
Siegbert Rieg
et al.
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966-974
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| Dermatopathology |
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Cutaneous and mucosal mucormycosis mimicking pancreatic panniculitis and gouty panniculitis
29 September 2011
Background: Histopathologic study of lesions of cutaneous mucormycosis usually shows suppurative granulomas involving the deep dermis and subcutaneous fat. Large, broad and non-septate fungal hyphae a...
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Luis Requena,
Panitta Sitthinamsuwan,
Carlos Santonja,
María Teresa Fernández-Figueras,
José Luis Rodríguez-Peralto,
Zsolt Argenyi,
Antonio Torrelo,
Lorenzo Cerroni,
Heinz Kutzner
et al.
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975-984
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| Dermatoethics Consultation |
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The unsolicited ominous diagnosis: Legal, moral, and ethical considerations
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Jane M. Grant-Kels,
Julia K. Anderson,
Barry D. Kels
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985-987
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| Reviews |
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A critical reappraisal of the current data on drug-induced linear immunoglobulin A bullous dermatosis: A real and separate nosological entity?
12 December 2011
Background: Linear IgA disease (LAD) has been associated with a variety of drugs over the past 30 years. Objective: To review current literature on all available cases of drug-induced LAD, in order to...
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Giulio Fortuna,
Julio Cesar Salas-Alanis,
Eugenio Guidetti,
M. Peter Marinkovich
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988-994
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Toxic epidermal necrolysis: Review of pathogenesis and management
12 December 2011
Toxic epidermal necrolysis (TEN) is a severe cutaneous drug reaction with a mortality rate of approximately 30%. The hallmark of TEN is widespread epidermal sloughing due to keratinocyte apoptosis. Mu...
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Andrew Downey,
Chris Jackson,
Nadia Harun,
Alan Cooper
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995-1003
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| Letters |
| Notes & Comments |
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Calcinosis cutis: An additional therapy to consider
To the Editor: Reiter et al provide a comprehensive review of treatment options for calcinosis cutis (CC). However, they do not discuss the role of hematopoietic stem cell transplantation (HSCT), a tr...
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Nicole F. Velez,
Jeffrey P. Callen,
Ruth Ann Vleugels
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1004-1005
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Reply
To the Editor: We thank Dr Velez and coauthors for their comments on our article, “Calcinosis cutis, part II: Treatment options.” Autologous stem cell transplantation (ASCT) exerts a positive effect o...
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Nadine Reiter,
Elisabeth Aberer
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1005
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Evidence for fractional laser treatment in the improvement of cutaneous scars
To the Editor: We read with great interest the article by Tziotzios and colleagues describing strategies to reduce cutaneous scarring, published in January 2012. This valuable review article very brie...
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Kavitha K. Reddy,
Jeremy A. Brauer,
Roy G. Geronemus
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1005-1006
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Reply
To the Editor: We thank Dr Reddy et al for their comments and for suggesting a wider review of current evidence for the use of fractional lasers in the treatment of scars. The focus of our CME series ...
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Christos Tziotzios,
Christos Profyris,
Jane Sterling
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1006-1007
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| Research Letters |
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Stability of sunscreens and sunblocks following exposure to extreme temperatures
To the Editor: Sunscreens and sunblocks are significant means of protection from the cutaneous damages imparted by ultraviolet radiation (UVR). Chemical sunscreens, as opposed to physical sunblocks, t...
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Gordon W. Jung,
Patricia T. Ting,
Thomas G. Salopek
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1007-1009
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The infra-auricular fissure: A bedside marker of disease severity in patients with atopic dermatitis
To the Editor: Monitoring the severity of atopic dermatitis (AD) is crucial to disease management. Tools exist to assess disease severity for experimental studies; these tools are not practical in a h...
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Shawn G. Kwatra,
Hong Liang Tey,
Saba M. Ali,
Tushar Dabade,
Yiong-Huak Chan,
Gil Yosipovitch
et al.
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1009-1010
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Refusal of shingles vaccine: Implications for public health
To the Editor: While the varicella-zoster virus (VZV; chickenpox) vaccine (Varivax) is widely utilized and has produced a dramatic decline in VZV-related morbidity and mortality, the herpes zoster vir...
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Angela L. Funovits,
Kyle L. Wagamon,
Eliot N. Mostow,
Robert T. Brodell
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1011-1012
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Association between pediatric psoriasis and the metabolic syndrome
To the Editor: Psoriasis is an inflammatory skin disease that affects approximately 2% of the general population, and roughly 1% of children. Numerous large population-based studies have demonstrated ...
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Shiu-chung Au,
Ari M. Goldminz,
Daniel S. Loo,
Nicole Dumont,
Danielle Levine,
Eva Volf,
Melissa Michelon,
Andrew Wang,
Noori Kim,
Shimrat Yaniv,
Paul F. Lizzul,
Todd Kerensky,
Jorge M. Lopez-Benitez,
Marc Natter,
Laurie Miller,
Christina F. Pelajo,
Trevor Davis,
Alice B. Gottlieb
et al.
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1012-1013
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Lipodermatosclerosis: Improvement noted with hydroxychloroquine and pentoxifylline
To the Editor: Lipodermatosclerosis (LDS) is believed to be associated with chronic venous insufficiency. Abnormal fibrinolysis, the excessive proteolytic activity by matrix metalloproteinase, and the...
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Charoen Choonhakarn,
Suteeraporn Chaowattanapanit
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1013-1014
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| Case Letter |
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Dermatophytoma: Description of 7 cases
To the Editor: Dermatophytoma is a little-known microscopic manifestation of fungal nail infection only recently mentioned in the literature. It is characterized by abundant fungal filaments, large sp...
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Erick Martinez-Herrera,
Gabriela Moreno-Coutiño,
Ramon F. Fernández-Martínez,
Justin Finch,
Roberto Arenas
et al.
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1014-1016
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| Index to Volume 66 |
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Author(s) |
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Cover Sheet for Index
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1017-1018
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Author index∗
Aarons E (see Benton et al). 2012;66:e123-4 (Case letter)
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1019-1033
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Subject index
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1034-1057
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Dermatology Calendar
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1058
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| Images in Dermatology |
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Article Title |
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Linear erythematous papules from previous scratching
A 63-year-old man presented with erythematous papules in a linear distribution (). Each linear lesion persisted beyond 24 hours. He complained of severe itching but otherwise felt well. A complete blo...
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Corinna Hamsch,
Martin Hartmann
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e189-e190
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A scaling rash preferentially involving a recent tattoo
An 18-year-old woman developed an asymptomatic rash 2 weeks after having a tattoo applied that preferentially affected both the red and black areas of the tattoo. There was no history of a sore throat...
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Vindhya Veerula,
Jenifer R. Lloyd,
Robert T. Brodell
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e191-e192
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| JAAD Online |
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An appraisal of oral retinoids in the treatment of pachyonychia congenita
23 May 2011
Background: Pachyonychia congenita (PC), a rare autosomal-dominant keratin disorder caused by mutations in keratin genes KRT6A/B, KRT16, or KRT17, is characterized by painful plantar keratoderma and h...
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Robert Gruber,
Michael Edlinger,
Roger L. Kaspar,
C. David Hansen,
Sancy Leachman,
Leonard M. Milstone,
Frances J.D. Smith,
Alexis Sidoroff,
Peter O. Fritsch,
Matthias Schmuth
et al.
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e193-e199
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Neuropeptide Y expression in cutaneous melanoma
27 May 2011
Background: Neuropeptide Y (NPY) is widely found in the nervous system and has a role in numerous physiologic processes. In addition, NPY receptors are expressed in neuroendocrine tumors, breast cance...
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Yolanda Gilaberte,
M. Jose Roca,
M. Dolores Garcia-Prats,
Carmen Coscojuela,
M. Dolores Arbues,
Jesús J. Vera-Alvarez
et al.
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e201-e208
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A randomized, investigator-blinded, controlled pilot study to evaluate the safety and efficacy of a poly-N-acetyl glucosamine–derived membrane material in patients with venous leg ulcers
27 May 2011
Background: Standard care for venous leg ulcers (VLUs) has remained unchanged over several decades despite high rates of initial treatment failure and ulcer recurrence. Objective: We sought to evaluat...
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Teresa J. Kelechi,
Martina Mueller,
Cheryl S. Hankin,
Amy Bronstone,
John Samies,
Phyllis A. Bonham
et al.
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e209-e215
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Chronic mucocutaneous herpes simplex virus and varicella zoster virus infections
09 November 2010
Chronic herpes simplex virus (CHSV) and chronic varicella zoster virus (CVZV) are defined as atypical mucocutaneous wart-like and/or ulcerative HSV or VZV infections, persisting for at least 1 month. ...
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Odile Wauters,
Eglantine Lebas,
Arjen F. Nikkels
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e217-e227
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A review of DRESS-associated myocarditis
09 June 2011
DRESS (drug rash with eosinophilia and systemic symptoms), also known as drug-induced hypersensitivity syndrome, is a severe, systemic drug reaction most commonly associated with aromatic anticonvulsa...
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Greg P. Bourgeois,
Jennifer A. Cafardi,
Vlada Groysman,
Lauren C. Hughey
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e229-e236
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Chemical leukoderma after the application of a transdermal methylphenidate patch
To the Editor: Chemical leukoderma is a chemically induced acquired hypopigmented dermatosis. We report a case of chemical leukoderma induced by a transdermal methylphenidate medicated patch for the t...
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Pedram Ghasri,
Shilpa Gattu,
Naz Saedi,
Anand K. Ganesan
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e237-e238
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Blastic plasmacytoid dendritic cell neoplasm in a child
To the Editor: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) has been described as a distinct clinicopathologic entity in the last World Health Organization classification of tumors of hematopo...
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Carla Ferrándiz-Pulido,
Ingrid López-Lerma,
Constantino Sábado,
Berta Ferrer,
Sandra Pisa,
Vicente García-Patos
et al.
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e238-e240
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Mycosis fungoides–associated follicular mucinosis after bone-marrow transplantation
To the Editor: A 32-year-old woman with acute myelogenous leukemia presented with a 2-month history of subtle papules on her cheeks and forehead 100 days after allogenic bone-marrow transplantation ()...
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Faith A. Stewart,
Aleodor Andea,
Lauren C. Hughey
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e240-e241
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Onychopapilloma presenting as longitudinal melanonychia
To the Editor: Onychopapilloma is a benign neoplasm of the distal matrix and the nail bed.
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Mariya Miteva,
Piero A. Fanti,
Paolo Romanelli,
Martin Zaiac,
Antonella Tosti
et al.
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e242-e243
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Pemphigus foliaceus clearance status postmyomectomy for an enlarged infarcted subserous uterine fibroid
To the Editor: Pemphigus foliaceus is a well-defined clinical disease that has been linked to thymic neoplasmsm; however, most cases are idiopathic in origin. The purpose of this letter is to describe...
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Samantha H. Fisher,
Ann A. Church,
Christina L. Mitchell,
Carlos H. Nousari
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e243-e245
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Nodular scleroderma presenting as multiple spontaneous keloidal scars
To the Editor: A 13-year-old African American girl presented with a history of several keloidal scars arising in areas of previously normal-appearing skin involving the face, neck, trunk, and lower an...
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Candrice R. Heath,
Jennifer N. David,
Susan C. Taylor
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e245-e246
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Multiple cutaneous metastatic chordomas from the sacrum
To the Editor: A 78-year-old woman with a history of sacral chordoma presented 2 years after wide local resection with multiple rubbery, flesh-colored, nodular lesions of the scalp measuring 0.9 × 0.7...
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Ryan M. Svoboda,
Donald Mackay,
Michael Jude Welsch,
Bryan E. Anderson
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e246-e247
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Mycobacterium celatum skin infection with sporotrichoid spread in an HIV-negative immunocompromised man
To the Editor: A 68-year-old man presented with a 2-month history of progressing plaques on his right arm after he had punctured the tip of his fourth finger with a fishhook. A first plaque had appear...
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Jean-Michel Leduc,
Simon F. Dufresne,
Christian Lavallée,
Simon Nigen,
Annie-Claude Labbé,
Louise Poirier
et al.
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e247-e249
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Successful treatment of lamotrigine-associated drug hypersensitivity syndrome with intravenous IgG
To the Editor: Anticonvulsant hypersensitivity syndrome is an adverse and potentially fatal condition associated with the use of certain anticonvulsants. It is characterized by the presence of fever, ...
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Nneka I. Comfere,
Julio C. Sartori-Valinotti,
Alison J. Bruce,
Lisa A. Drage
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e249-e250
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Galli-Galli disease is an acantholytic variant of Dowling-Degos disease: Additional genetic evidence in a German family
To the Editor: Dowling-Degos disease (DDD) is a rare autosomal dominant genodermatosis with variable penetrance. It is characterized by reticular hyperpigmentation and pruritic follicular hyperkeratot...
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Astrid Schmieder,
Sandra M. Pasternack,
Dieter Krahl,
Regina C. Betz,
Martin Leverkus
et al.
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e250-e251
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A case of rapid improvement of severe psoriasis during molecular-targeted therapy using an epidermal growth factor receptor tyrosine kinase inhibitor for metastatic lung adenocarcinoma
To the Editor: We describe a patient with severe psoriasis whose skin lesions regressed after the oral administration of erlotinib, an epidermal growth factor receptor (EGFR)-specific tyrosine kinase ...
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Noritaka Oyama,
Fumio Kaneko,
Ari Togashi,
Toshiyuki Yamamoto
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e251-e253
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Aesthetic rejuvenation: A regional approach
Aesthetic Rejuvenation: A Regional Approach edited by Ranell Hirsch, Neil Sadick, and Joel L. Cohen is a lightweight, but comprehensive, easy-to-use textbook. The book's focus is on specific regions o...
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Theresa Conologue
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e255
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The cutaneous lymphoid proliferations: A comprehensive textbook of lymphocytic infiltrates of the skin
Magro et al have succeeded in filling a vacuum in our libraries. This is the first truly comprehensive book on the subject of lymphoid-rich infiltrates of the skin covering the entire spectrum of cuta...
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Joan Guitart
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e255-e256
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History of German language dermatology
In the late decades of the 18th century, the ravages of syphilis and other contagions aroused widespread public alarm. Syphilis and other venereal diseases were rampant. Scabies was endemic. Many diso...
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Robert W. Goltz
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e256-e257
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Consultant pathology: Tumorigenic melanocytic proliferations
Tumorigenic melanocytic proliferations, by David Elder, is part of the Consultant Pathology series published by Demos Medical Publishing. Given that most medical titles are now published by Elsevier o...
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Dirk M. Elston
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e257-e258
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Psoriasis
Another book dedicated to psoriasis is always welcomed, especially if it is current and meticulously updated by a renowned authority and his colleague. Psoriasis is such a book, and it is succinct, co...
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Charles Camisa
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e258
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Iotaderma #221
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Robert I. Rudolph
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e259
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